Evidence map›Paper›PMID 38539635›Full record

ArticleBrain sciences2024

White Matter Integrity and Motor Function Disruption Due to Traumatic Brain Injury in Piglets: Impacts on Motor-Related Brain Fibers.

Madison M Fagan, Kelly M Scheulin, Sydney E Sneed, Wenwu Sun, Christina B Welch, Savannah R Cheek, Erin E Kaiser, Qun Zhao, Kylee J Duberstein, Franklin D West

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Blockade of Presynaptic αNeurochemical research · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Madison M FaganRegenerative Bioscience Center, University of Georgia, 425 River Rd., Athens, GA 30602, USA.
Kelly M ScheulinRegenerative Bioscience Center, University of Georgia, 425 River Rd., Athens, GA 30602, USA.
Sydney E SneedRegenerative Bioscience Center, University of Georgia, 425 River Rd., Athens, GA 30602, USA.
Wenwu SunRegenerative Bioscience Center, University of Georgia, 425 River Rd., Athens, GA 30602, USA.
Christina B WelchDepartment of Animal and Dairy Science, College of Agriculture and Environmental Science, University of Georgia, 425 River Rd., Athens, GA 30602, USA.ORCID 0000-0001-9837-9677
Savannah R CheekDepartment of Animal and Dairy Science, College of Agriculture and Environmental Science, University of Georgia, 425 River Rd., Athens, GA 30602, USA.
Erin E KaiserRegenerative Bioscience Center, University of Georgia, 425 River Rd., Athens, GA 30602, USA.
Qun ZhaoRegenerative Bioscience Center, University of Georgia, 425 River Rd., Athens, GA 30602, USA.ORCID 0000-0003-0784-1024
Kylee J DubersteinRegenerative Bioscience Center, University of Georgia, 425 River Rd., Athens, GA 30602, USA.
Franklin D WestRegenerative Bioscience Center, University of Georgia, 425 River Rd., Athens, GA 30602, USA.ORCID 0000-0002-0504-7997

Funding

University of Georgia Innovative and Interdisciplinary Research Grant, the Franklin Foundation for Neuroimaging, and the College of Agriculture and Environmental Sciences, University of Georgia. XXX
6 · The paper itself

Abstract

Pediatric traumatic brain injury (TBI) often induces significant disability in patients, including long-term motor deficits. Early detection of injury severity is key in determining a prognosis and creating appropriate intervention and rehabilitation plans. However, conventional magnetic resonance imaging (MRI) scans, such as T2 Weighted (T2W) sequences, do not reliably assess the extent of microstructural white matter injury. Diffusion tensor imaging (DTI) tractography enables three-dimensional reconstruction of specific white matter tracts throughout the brain in order to detect white matter injury based on anisotropic diffusion. The objective of this study was to employ DTI tractography to detect acute changes to white matter integrity within the intersecting fibers of key motor-related brain regions following TBI. Piglets were assigned to either the sham craniectomy group (sham;

Indexed as

diffusion tensor imagingmotor functionpediatric TBIpiglet model

Identifiers

PMID38539635
PMCPMC10969094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.