Evidence map›Paper›PMID 38539632›Full record

ArticleBrain sciences2024

Oxygen-Glucose Deprivation Increases NR4A1 Expression and Promotes Its Extranuclear Translocation in Mouse Astrocytes.

Kengo Moriyama, Asako Horino, Kuniko Kohyama, Yasumasa Nishito, Tomohiro Morio, Hiroshi Sakuma

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Vasopressin-Sensitive Aqp2 Regulation Mediated by the TAZ-NR4A1 Axis in Renal Collecting Duct Cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kengo MoriyamaDepartment of Brain and Neuroscience, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.ORCID 0000-0002-9275-9334
Asako HorinoDepartment of Brain and Neuroscience, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Kuniko KohyamaDepartment of Brain and Neuroscience, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Yasumasa NishitoTechnology Research Division, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Tomohiro MorioDepartment of Pediatrics, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Hiroshi SakumaDepartment of Brain and Neuroscience, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Tokyo Metropolitan Institute of Medical Science · JPTokyo Medical and Dental University · JP

Funding

Japan Society for the Promotion of Science 19K08311
6 · The paper itself

Abstract

Hypoxic-ischemic brain injury induces metabolic dysfunction that ultimately leads to neuronal cell death. Astrocytes, a type of glial cell, play a key role in brain metabolism; however, their response to hypoxic-ischemic brain injury is not fully understood. Microglia were removed from murine primary mixed glial cultures to enrich astrocytes. Next, we explored genes whose expression is altered following oxygen-glucose deprivation using a microarray. Microarray analysis revealed that the expression of

Indexed as

CDIM8HIF-1αmitochondriaNR4A1NR4A3oxygen–glucose deprivationpexidartinibreoxygenation

Identifiers

PMID38539632
PMCPMC10968342
OpenAlexW4392355945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.