Evidence map›Paper›PMID 38539563›Full record

ArticleCancers2024

Treatment Strategies for Glioblastoma in the Elderly: What Should We Focus on Compared to Younger Patients.

Hanah Hadice Gull, Antonia Carlotta Von Riegen, Greta Theresa Beckmann, Pikria Ketelauri, Sebastian Walbrodt, Alejandro N Santos, Christoph Oster, Teresa Schmidt, Martin Glas, Ramazan Jabbarli and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Hanah Hadice GullDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0002-0483-4243
Antonia Carlotta Von RiegenDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0009-0008-9525-3567
Greta Theresa BeckmannDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0009-0006-4651-0876
Pikria KetelauriDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Sebastian WalbrodtDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Alejandro N SantosDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Christoph OsterDKFZ-Division Translational Neurooncology at the WTZ, DKTK Partner Site, University Hospital Essen, 45147 Essen, Germany.ORCID 0000-0002-0683-0430
Teresa SchmidtDKFZ-Division Translational Neurooncology at the WTZ, DKTK Partner Site, University Hospital Essen, 45147 Essen, Germany.
Martin GlasCenter for Translational Neuro- and Behavioral Sciences (C-TNBS), University of Duisburg-Essen, 45147 Essen, Germany.
Ramazan JabbarliDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0002-8356-6629
Neriman ÖzkanDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Philipp DammannDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Björn SchefflerDKFZ-Division Translational Neurooncology at the WTZ, DKTK Partner Site, University Hospital Essen, 45147 Essen, Germany.
Ulrich SureDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0002-9073-1821
Yahya AhmadipourDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0003-3759-8301
University of Duisburg-Essen · DEWest German Heart and Vascular Center Essen · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Although the incidence of glioblastoma (GB) has a peak in patients aged 75-84 years, no standard treatment regimen for elderly patients has been established so far. The goal of this study was to analyze the outcome of GB patients ≥ 65 years to detect predictors with relevant impacts on overall survival (OS) and progression-free survival (PFS). (2) Methods: Medical records referred to our institution from 2006 to 2020 were analyzed. Adult GB patients with clinical data, postoperative MRI data, and ≥1 follow-up investigation after surgical resection were included. The complete cohort was divided into a younger (<65) and an elderly group (≥65 years). Multiple factors regarding OS and PFS were scanned using univariate and multivariable regression with

Indexed as

elderly glioblastoma patientselderly patientsglioblastomaoverall survivalprogression-free survival

Identifiers

PMID38539563
PMCPMC10968885
OpenAlexW4393045995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.