ArticleCancers2024
Clinical Workflow of Cone Beam Computer Tomography-Based Daily Online Adaptive Radiotherapy with Offline Magnetic Resonance Guidance: The Modular Adaptive Radiotherapy System (MARS).
Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- The current state of demographic subgroup reporting for commercially available AI for radiology: a scoping review.European radiology · 2026Article
- MRI-enhanced online adaptive radiotherapy by virtual integration of a standalone MRI simulator and CBCT-based treatment delivery.Radiation oncology (London, England) · 2026Article
- Towards a shuttle-based workflow for daily online magnetic resonance imaging-guided particle therapy: Anatomical robustness and organ variability in the female pelvis.Technical innovations & patient support in radiation oncology · 2026Article
- Interpretable QSAR and Complementary Docking for PARP1 Inhibitor Prioritization: Reliability Stratification and Near-Domain Screening.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Long-term patient experience with online MR-guided radiotherapy: adaptive versus non-adaptive workflow.Frontiers in oncology · 2026Article
- [Simulation-free radiation therapy in palliative care].Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- Stability of liver position in a shuttle-based workflow for daily online magnetic resonance imaging-guided particle therapy.Physics and imaging in radiation oncology · 2025Article
- Article
- Analysis of intra-fractional surface motion during adaptive radiation therapy and relation of internal vs. external position for prostate cancer.Radiation oncology (London, England) · 2025Article
- A quantitative analysis of artificial intelligence research in cervical cancer: a bibliometric approach utilizing CiteSpace and VOSviewer.Frontiers in oncology · 2024Article
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Authors and funding
15 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThe Ethos (Varian Medical Systems) radiotherapy device combines semi-automated anatomy detection and plan generation for cone beam computer tomography (CBCT)-based daily online adaptive radiotherapy (oART). However, CBCT offers less soft tissue contrast than magnetic resonance imaging (MRI). This work aims to present the clinical workflow of CBCT-based oART with shuttle-based offline MR guidance.
methodsFrom February to November 2023, 31 patients underwent radiotherapy on the Ethos (Varian, Palo Alto, CA, USA) system with machine learning (ML)-supported daily oART. Moreover, patients received weekly MRI in treatment position, which was utilized for daily plan adaptation, via a shuttle-based system. Initial and adapted treatment plans were generated using the Ethos treatment planning system. Patient clinical data, fractional session times (MRI + shuttle transport + positioning, adaptation, QA, RT delivery) and plan selection were assessed for all fractions in all patients.
resultsIn total, 737 oART fractions were applied and 118 MRIs for offline MR guidance were acquired. Primary sites of tumors were prostate (
conclusionThis study describes the first workflow to date of a CBCT-based oART combined with a shuttle-based offline approach for MR guidance. The oART duration times reported resemble the range shown by previous publications for first clinical experiences with the Ethos system.
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