Evidence map›Paper›PMID 38539542›Full record

ReviewCancers2024

Current Treatment Options for Renal Cell Carcinoma: Focus on Cell-Based Immunotherapy.

Angela Hwang, Vedika Mehra, Jyoti Chhetri, Samira Ali, Maxine Tran, Claire Roddie

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Prognostic Value of the Lung Immune Prognostic Index in Metastatic Renal Cell Carcinoma Treated With Second-Line Immunotherapy.International journal of urology : official journal of the Japanese Urological Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Angela HwangDepartment of Haematology, University College Hospital, University College London Hospitals NHS Foundation Trust, London NW1 2BU, UK.ORCID 0009-0004-4938-0910
Vedika MehraUniversity College London Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK.
Jyoti ChhetriUniversity College London Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK.
Samira AliUniversity College London Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK.
Maxine TranUniversity College London Division of Surgery and Interventional Science, Rowland Street, London NW3 2QG, UK.
Claire RoddieDepartment of Haematology, University College Hospital, University College London Hospitals NHS Foundation Trust, London NW1 2BU, UK.ORCID 0000-0002-4901-5858
London Cancer · GBUniversity College Hospital · GBThe Royal Free Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) affects over 400,000 patients globally each year, and 30% of patients present with metastatic disease. Current standard of care therapy for metastatic RCC involve TKIs and ICIs, including combinatorial strategies, but this offers only modest clinical benefit. Novel treatment approaches are warranted, and cell-based immunotherapies for RCC hold significant promise. These are currently being tested in the pre-clinical setting and in early phase clinical trials. Here, we review the landscape of cellular immunotherapy for RCC in the context of currently available therapies, with a particular focus on defining the current best antigenic targets, the range of cell therapy products being explored in RCC, and how advanced engineering solutions may further enhance these therapies in the RCC space.

Indexed as

chimeric antigen receptor (CAR) T-cellsengineered TCR T-cellsimmunotherapyrenal cell carcinoma

Identifiers

PMID38539542
PMCPMC10968958
OpenAlexW4392990823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.