Evidence map›Paper›PMID 38539532›Full record

ArticleCancers2024

Does Breast Surgery Type Alter Incidental Axillary Irradiation? A Dosimetric Analysis of the "Sentinel Envahi et Randomisation du Curage" SERC Trial.

Camille Nicolas, Claire Petit, Agnès Tallet, Jean-Marie Boher, Leonel Varela Cagetti, Veronique Favrel, Laurence Gonzague Casabianca, Morgan Guenole, Hugues Mailleux, Julien Darreon and 11 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Camille NicolasDepartment of Radiotherapy, Institut Paoli-Calmettes, 13009 Marseille, France.
Claire PetitDepartment of Radiotherapy, Institut Paoli-Calmettes, 13009 Marseille, France.
Agnès TalletDepartment of Radiotherapy, Institut Paoli-Calmettes, 13009 Marseille, France.
Jean-Marie BoherBiostatistics and Methodology Unit, Institut Paoli-Calmettes, INSERM (National Institute of Health and Medical Research), IRD (Development Research Institute), Aix Marseille University, 13009 Marseille, France.
Leonel Varela CagettiDepartment of Radiotherapy, Institut Paoli-Calmettes, 13009 Marseille, France.
Veronique FavrelDepartment of Radiotherapy, Institut Paoli-Calmettes, 13009 Marseille, France.
Laurence Gonzague CasabiancaDepartment of Radiotherapy, Institut Paoli-Calmettes, 13009 Marseille, France.
Morgan GuenoleDepartment of Radiotherapy, Institut Paoli-Calmettes, 13009 Marseille, France.
Hugues MailleuxDepartment of Medical Physic, Institut Paoli-Calmettes, 13009 Marseille, France.
Julien DarreonDepartment of Medical Physic, Institut Paoli-Calmettes, 13009 Marseille, France.
Marie BannierDepartment of Surgical Oncology, Institut Paoli-Calmettes, CRCM (Research Cancer Centre of Marseille), 13009 Marseille, France.
Monique CohenDepartment of Surgical Oncology, Institut Paoli-Calmettes, CRCM (Research Cancer Centre of Marseille), 13009 Marseille, France.
Laura SabianiDepartment of Surgical Oncology, Institut Paoli-Calmettes, CRCM (Research Cancer Centre of Marseille), 13009 Marseille, France.
Camille TalletFaculty of Medical and Paramedical Sciences, Medical School, Aix-Marseille University, 13005 Marseille, France.
Charlene TeyssandierFaculty of Medical and Paramedical Sciences, Medical School, Aix-Marseille University, 13005 Marseille, France.
Anthony GonçalvesDepartment of Medical Oncology, CNRS (National Center of Scientific Research), INSERM (National Institute of Health and Medical Research), Institut Paoli-Calmettes, CRCM (Research Cancer Centre of Marseille), Aix-Marseille University, 13009 Marseille, France.ORCID 0000-0001-7570-7439
Alexandre De NonnevilleDepartment of Medical Oncology, CNRS (National Center of Scientific Research), INSERM (National Institute of Health and Medical Research), Institut Paoli-Calmettes, CRCM (Research Cancer Centre of Marseille), Aix-Marseille University, 13009 Marseille, France.
Leonor Lopez AlmeidaDepartment of Clinical Research, Institut Paoli-Calmettes, 13009 Marseille, France.
Nathan CosteDepartment of Clinical Research, Institut Paoli-Calmettes, 13009 Marseille, France.
Marguerite TyranDepartment of Radiotherapy, Institut Paoli-Calmettes, 13009 Marseille, France.
Gilles HouvenaeghelDepartment of Surgical Oncology, CNRS (National Center of Scientific Research), INSERM (National Institute of Health and Medical Research), Institut Paoli-Calmettes, CRCM (Research Cancer Centre of Marseille), Aix-Marseille University, 13009 Marseille, France.ORCID 0000-0002-4384-6255
Institut Paoli-Calmettes · FRCentre de Recherche en Cancérologie de Marseille · FRCentre National de la Recherche Scientifique · FRAix-Marseille Université · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn incidental axillary dose of adjuvant radiotherapy using tangential beams is usually given after breast-conserving surgery for breast cancer. The goal of this sub-study was to evaluate this incidental dose in the setting of post-mastectomy radiotherapy (PMRT) according to two different radiotherapy techniques.

methodsPatients participating in a randomized SERC trial who received PMRT in a single center were included. We collected the incidental axillary dose delivered to the Berg level 1 using different dosimetric parameters and compared two techniques using Student's

resultsWe analyzed radiotherapy plans from 52 patients who received PMRT from 2012 to 2021. The mean dose delivered to the Berg level 1 was 37.2 Gy. It was significantly higher with VMAT than with 3D-CRT-43.6 Gy (SD = 3.1 Gy) versus 34.8 Gy (SD = 8.6 Gy)

conclusionsOn the Berg level 1, PMRT gives a dose at least equivalent to the one given by post-breast-conserving surgery radiotherapy, making it possible to limit completion axillary lymph node dissections in select pN1a patients treated with a mastectomy. Modern radiotherapy techniques like VMAT tend to increase this incidental dose.

Indexed as

axillary lymph nodesbreast cancermastectomyradiotherapy

Identifiers

PMID38539532
PMCPMC10969031
OpenAlexW4392960487

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.