Evidence map›Paper›PMID 38539450›Full record

ReviewCancers2024

Upper Tract Urothelial Cancer: Guideline of Guidelines.

Savio Domenico Pandolfo, Simone Cilio, Achille Aveta, Zhenjie Wu, Clara Cerrato, Luigi Napolitano, Francesco Lasorsa, Giuseppe Lucarelli, Paolo Verze, Salvatore Siracusano and 10 more

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06848868 (Flexible Ureterorenoscopy for Surveillance of Upper Tract Urothelial Carcinoma-A Pilot Study), which is not on this map. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
24.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06848868 phase1recruitingnot on this mapstarted 2025, after this paper: background citation

Flexible Ureterorenoscopy for Surveillance of Upper Tract Urothelial Carcinoma-A Pilot Study

TypeinterventionalSponsorChinese University of Hong KongRan2025 to 2029Enrolled10ConditionsUpper Tract Urothelial CarcinomaArmsAmbulatory flexible ureterorenoscopy
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 14 institutions in 4 countries.

Savio Domenico PandolfoDepartment of Urology, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0001-9621-3059
Simone CilioDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0002-8431-9830
Achille AvetaDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0001-8470-1995
Zhenjie WuDepartment of Urology, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Clara CerratoUrology Unit, University Hospital of Southampton NHS Trust, Southampton S016 6YD, UK.ORCID 0000-0002-5013-7617
Luigi NapolitanoDepartment of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0003-2036-0356
Francesco LasorsaDepartment of Precision and Regenerative Medicine and Ionian Area-Urology, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0001-8884-0757
Giuseppe LucarelliDepartment of Precision and Regenerative Medicine and Ionian Area-Urology, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0001-7807-1229
Paolo VerzeDepartment of Medicine and Surgery, Scuola Medica Salernitana, University of Salerno, 84084 Fisciano, Italy.
Salvatore SiracusanoDepartment of Urology, University of L'Aquila, 67100 L'Aquila, Italy.
Carmelo QuattroneUnit of Urology, Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Matteo FerroDivision of Urology, IRCCS-European Institute of Oncology, 20141 Milan, Italy.
Eugenio BolognaDepartment of Maternal-Child and Urological Sciences, Sapienza University Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.ORCID 0000-0002-1140-0590
Riccardo CampiUrological Robotic Surgery and Renal Transplantation Unit, Careggi Hospital, University of Florence, 50121 Firenze, Italy.ORCID 0000-0001-5237-0888
Francesco Del GiudiceDepartment of Maternal-Child and Urological Sciences, Sapienza University Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy.ORCID 0000-0003-3865-5988
Riccardo BertoloDepartment of Urology, University of Verona, 37126 Verona, Italy.ORCID 0000-0003-0260-4601
Daniele AmparoreDivision of Urology, Department of Oncology, School of Medicine, University of Turin, San Luigi Hospital, Orbassano, 10043 Turin, Italy.ORCID 0000-0001-5425-5453
Sara PalumboDepartment of Molecular Medicine and Medical Biotechnologies, 80131 Naples, Italy.
Celeste ManfrediUnit of Urology, Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-9706-8516
Riccardo AutorinoDepartment of Urology, Rush University Medical Center, Chicago, IL 60612, USA.ORCID 0000-0001-7045-7725
University of Naples Federico II · ITPoliclinico Umberto I · ITUniversity of Bari Aldo Moro · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of L'Aquila · ITEuropean Institute of Oncology · ITInstitute of Biomembranes, Bioenergetics and Molecular Biotechnologies · ITRush University Medical Center · USSecond Military Medical University · CNUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Florence · ITUniversity of Salerno · ITUniversity of Turin · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUpper tract urothelial carcinoma (UTUC) is a rare disease with a potentially dismal prognosis. We systematically compared international guidelines on UTUC to analyze similitudes and differences among them.

methodsWe conducted a search on MEDLINE/PubMed for guidelines related to UTUC from 2010 to the present. In addition, we manually explored the websites of urological and oncological societies and journals to identify pertinent guidelines. We also assessed recommendations from the International Bladder Cancer Network, the Canadian Urological Association, the European Society for Medical Oncology, and the International Consultation on Bladder Cancer, considering their expertise and experience in the field.

resultsAmong all the sources, only the American Urologist Association (AUA), European Association of Urology (EAU), and the National Comprehensive Cancer Network (NCCN) guidelines specifically report data on diagnosis, treatment, and follow-up of UTUC. Current analysis reveals several differences between all three sources on diagnostic work-up, patient management, and follow-up. Among all, AUA and EAU guidelines show more detailed indications.

conclusionsDespite the growing incidence of UTUC, only AUA, EAU, and NCCN guidelines deal with this cancer. Our research depicted high variability in reporting recommendations and opinions. In this regard, we encourage further higher-quality research to gain evidence creating higher grade consensus between guidelines.

Indexed as

diagnosisfollow-upguidelinesmanagementupper tract urothelial carcinoma (UTUC)

Identifiers

PMID38539450
PMCPMC10969327
OpenAlexW4392660400

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.