Evidence map›Paper›PMID 38539402›Full record

ReviewChildren (Basel, Switzerland)2024

Review of Opsoclonus-Myoclonus Ataxia Syndrome in Pediatric Patients.

Mandy Hsu, Isbaah Tejani, Nidhi Shah, Rasaq Olaosebikan, Ashutosh Kumar, Sunil Naik

Open access · goldAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Mandy HsuUniversity Park Program, Penn State College of Medicine, State College, PA 16803, USA.
Isbaah TejaniMedical College, Aga Khan University, Karachi P.O. Box 8842, Pakistan.ORCID 0000-0002-4235-1357
Nidhi ShahDepartment of Pediatric Hematology/Oncology, Penn State Health Milton S. Hershey Medical Center, Hershey, PA 17033, USA.
Rasaq OlaosebikanDepartment of Pediatric Hematology/Oncology, Penn State Health Milton S. Hershey Medical Center, Hershey, PA 17033, USA.
Ashutosh KumarDepartment of Pediatric Neurology, Penn State Health Milton S. Hershey Medical Center, Hershey, PA 17033, USA.ORCID 0000-0002-4949-1395
Sunil NaikDepartment of Pediatric Neurology, Penn State Health Milton S. Hershey Medical Center, Hershey, PA 17033, USA.ORCID 0000-0002-0482-4547
Penn State Milton S. Hershey Medical Center · USAga Khan University · PKPennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opsoclonus-myoclonus ataxia syndrome (OMAS), also known as Kinsbourne syndrome, is a rare disorder that presents with myoclonus, ataxia, abnormal eye movements, irritability, and sleep disruptions, often in young children. We report a case of an infant barely 6 months old, with no significant past medical history, who presented to the emergency department with tremors, jerking motions of the head and arms, and rapid eye movements. After an extensive workup, she was found to have a neuroblastoma, which was subsequently surgically removed via thoracotomy. Despite an initial improvement in symptoms post-resection, the patient's symptoms recurred. She was subsequently treated with dexamethasone, intravenous immunoglobulin (IVIG), and rituximab. After treatment, the patient was noted to have mild global developmental delays but was otherwise well. This case report highlights the rare occurrence of OMAS in an infant barely 6 months old at diagnosis. Using the PubMed database, a systematic review was conducted to highlight the clinical presentation, diagnosis, and management of OMAS.

Indexed as

dancing eye dancing feet syndromeIVIGKinsbourne syndromeneuroblastomaopsoclonus-myoclonus ataxia syndromeparaneoplastic syndromepediatricrituximab

Identifiers

PMID38539402
PMCPMC10968807
OpenAlexW4393003244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.