Evidence map›Paper›PMID 38539395›Full record

ArticleChildren (Basel, Switzerland)2024

Neurofilament Light Chain Concentration in Cerebrospinal Fluid in Children with Acute Nontraumatic Neurological Disorders.

Tobias Geis, Svena Gutzeit, Sigrid Disse, Jens Kuhle, Sotiris Fouzas, Sven Wellmann

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Tobias GeisUniversity Children's Hospital Regensburg (KUNO) at the Hospital St. Hedwig of the Order of St. John, University of Regensburg, 93049 Regensburg, Germany.ORCID 0000-0002-6941-3247
Svena GutzeitUniversity Children's Hospital Regensburg (KUNO) at the Hospital St. Hedwig of the Order of St. John, University of Regensburg, 93049 Regensburg, Germany.
Sigrid DisseUniversity Children's Hospital Regensburg (KUNO) at the Hospital St. Hedwig of the Order of St. John, University of Regensburg, 93049 Regensburg, Germany.
Jens KuhleDepartment of Neurology, University Hospital, University of Basel, 4001 Basel, Switzerland.
Sotiris FouzasDepartment of Pediatrics, University Hospital of Patras, 265 04 Patras, Greece.ORCID 0000-0001-7617-9076
Sven WellmannDepartment of Neonatology, University Children's Hospital Regensburg (KUNO) at the Hospital St. Hedwig of the Order of St. John, University of Regensburg, 93049 Regensburg, Germany.ORCID 0000-0001-9230-6266
University of Regensburg · DEGeneral University Hospital of Patras · GRUniversity Hospital Regensburg · DEUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Introduction: This pilot study aimed to analyze neurofilament light chain levels in cerebrospinal fluid (cNfL) in a cohort of children with different acute nontraumatic neurological conditions. (2) Methods: This prospective observational cohort study consisted of 35 children aged 3 months to 17 years and was performed from November 2017 to December 2019. Patients' clinical data were reviewed, and patients were assigned to the following groups:

Indexed as

Bell’s facial palsybiomarkerchildLyme neuroborreliosis LNBmeningitisneurofilament light chain NfL

Identifiers

PMID38539395
PMCPMC10969464
OpenAlexW4392957499

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.