Evidence map›Paper›PMID 38539384›Full record

ArticleChildren (Basel, Switzerland)2024

The Risks of Phosphate Enemas in Toddlers: A Life-Threatening Unawareness.

Alessandro Zago, Alessandro Agostino Occhipinti, Matteo Bramuzzo, Viola Ceconi, Vincenzo Colacino, Egidio Barbi, Federico Poropat

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Iatrogenic neonatal hyperphosphatemia due to phosphate-containing enema.Endocrinology, diabetes & metabolism case reports · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alessandro ZagoDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34149 Trieste, Italy.ORCID 0000-0003-3465-6676
Alessandro Agostino OcchipintiDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Matteo BramuzzoDepartment of Pediatrics, Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0002-5249-8248
Viola CeconiDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Vincenzo ColacinoAzienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.
Egidio BarbiDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34149 Trieste, Italy.ORCID 0000-0002-6343-846X
Federico PoropatDepartment of Pediatrics, Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0003-1554-3174
University of Trieste · ITIRCCS Materno Infantile Burlo Garofolo · IT

Funding

Ministero della Salute N/A
6 · The paper itself

Abstract

backgroundWhile oral laxatives represent the first-line treatment of fecal impaction, enemas are frequently used in clinical practice in pediatric emergency departments (PEDs) and by family pediatricians (FPs).

objectivesPhosphate-containing enemas (PcEs) are commonly employed, even causing the risk of rare but lethal toxicity. We investigated pediatricians' awareness of PcE risks.

methodsWe conducted an online survey by sending a multiple-choice questionnaire to the referents of 51 PEDs and 101 FPs. We collected and compared the answers with recommendations reported by the Italian Drug Agency (AIFA) and the available literature about PcE administration.

resultsOf the institutions and pediatricians receiving the questionnaire, 23 PEDs (45%) and 63 FP (62.3%) participated in the survey. Of PEDs, 95% and 33.0% of FPs treated fecal impaction with PcE. Moreover, 54% of PEDs and 86.0% of FPs did not provide treatment according to the AIFA recommendations for the daily dose.

conclusionsThis study shows limited pediatricians' awareness of the potential risks related to PcE.

Indexed as

constipationpediatric gastroenterologyphosphate-containing enemasside effects

Identifiers

PMID38539384
PMCPMC10968950
OpenAlexW4392845626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.