Evidence map›Paper›PMID 38539379›Full record

ArticleChildren (Basel, Switzerland)2024

Generalized Joint Hypermobility: A Statistical Analysis Identifies Non-Axial Involvement in Most Cases.

Mateus Marino Lamari, Neuseli Marino Lamari, Michael Peres de Medeiros, Matheus Gomes Giacomini, Adriana Barbosa Santos, Gerardo Maria de Araújo Filho, Eny Maria Goloni-Bertollo, Érika Cristina Pavarino

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mateus Marino LamariDepartment of Epidemiology and Public Health, Medical School of São José do Rio Preto (FAMERP), Av. Brigadeiro Faria Lima, 5416, Vila São Pedro, São José do Rio Preto 15090-000, SP, Brazil.
Neuseli Marino LamariDepartment of Neurological Sciences, Psychiatry and Medical Psychology, Medical School of São José do Rio Preto (FAMERP), Av. Brigadeiro Faria Lima, 5416, Vila São Pedro, São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0003-2211-1054
Michael Peres de MedeirosDepartment of Neurological Sciences, Psychiatry and Medical Psychology, Medical School of São José do Rio Preto (FAMERP), Av. Brigadeiro Faria Lima, 5416, Vila São Pedro, São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0003-2269-9812
Matheus Gomes GiacominiFoundation of the Regional Medical School of São José do Rio Preto (FUNFARME), Av. Brigadeiro Faria Lima, 5544, Vila São Pedro, São José do Rio Preto 15090-000, SP, Brazil.
Adriana Barbosa SantosDepartment of Computer Science and Statistics, São Paulo State University (UNESP), R. Cristóvão Colombo, 2265, Jardim Nazareth, São José do Rio Preto 15054-000, SP, Brazil.
Gerardo Maria de Araújo FilhoDepartment of Neurological Sciences, Psychiatry and Medical Psychology, Medical School of São José do Rio Preto (FAMERP), Av. Brigadeiro Faria Lima, 5416, Vila São Pedro, São José do Rio Preto 15090-000, SP, Brazil.
Eny Maria Goloni-BertolloGenetics and Molecular Biology Research Unit, Department of Molecular Biology, Medical School of São José do Rio Preto (FAMERP), Av. Brigadeiro Faria Lima, 5416, Vila São Pedro, São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0002-2622-4673
Érika Cristina PavarinoGenetics and Molecular Biology Research Unit, Department of Molecular Biology, Medical School of São José do Rio Preto (FAMERP), Av. Brigadeiro Faria Lima, 5416, Vila São Pedro, São José do Rio Preto 15090-000, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextJoint hypermobility (JH) represents the extreme of the normal range of motion or a condition for a group of genetically determined connective tissue disorders. Generalized joint hypermobility (GJH) is suspected when present in all four limbs and the axial skeleton, scored in prepubescent children and adolescents by a Beighton Score (BS) ≥ 6. Parameters are also used to identify GJH in hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSDs). The purpose of this study is to characterize children with JH based on the location of variables in the BS ≥ 6 and identify children with JH in the axial skeleton, upper limbs (ULs), and lower limbs (LLs) simultaneously.

methodsWe analyzed 124 medical records of one- to nine-year-old children with JH by BS.

resultsThe characterization of GJH by combinations of the axial skeleton, ULs, and LLs simultaneously totaled 25.7%. BS = 6 and BS = 8 consisted of variables located in ULs and LLs. BS = 7 included the axial skeleton, ULs, and LLs. BS ≥ 6 represents the majority of the sample and predominantly girls.

conclusionsBS ≥ 6 represents the majority of the sample and predominantly girls. Most characterized children with GJH present BS = 6 and BS = 8 with variables located only in ULs and LLs, a condition that does not imply the feature is generalized. In children, BS = 7 and BS = 9 characterize GJH by including the axial skeleton, ULs, and LLs. These results draw attention to the implications for defining the diagnosis of hEDS and HSDs.

Indexed as

childEhlers–Danlos syndromehypermobility spectrum disordersjoint hypermobilitypediatrics

Identifiers

PMID38539379
PMCPMC10969682

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