Evidence map›Paper›PMID 38539029›Full record

ArticleVeterinary research communications2024

Evaluation of in-feed supplementation of formic acid and thymol as non-antibiotic growth promoters and assessing their effect on antimicrobial resistant E.coli isolated in Turkey.

Abhijeet Champati, Subrat Kumar Bhanja, Jaydip Jaywant Rokade, Nibedita Nayak, Ajit Singh Yadav, Avishek Biswas, Divya Sharma, Juli Chakma, Sky, Jyotiprabha Mishra and 3 more

Abstract read
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In one paragraph

Article in Veterinary research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Abhijeet ChampatiICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India. abhijeetchampati92@gmail.com.
Subrat Kumar BhanjaICAR-Directorate of Poultry Research, Regional Station, Bhubaneswar, Odisha, 751003, India. subratcari@gmail.com.
Jaydip Jaywant RokadeICAR-Central Avian Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.
Nibedita NayakICAR-Central Coastal Agricultural Research Institute, Goa, 403402, India.
Ajit Singh YadavIndian Council of Agricultural Research (ICAR), New Delhi, 110001, India.
Avishek BiswasICAR-Central Institute for Research on Cattle, Meerut, Uttar Pradesh, 250001, India.
Divya SharmaICAR-Central Avian Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.
Juli ChakmaICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.
SkyICAR-Central Avian Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.
Jyotiprabha MishraICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.
Subodh Kumar SahaICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.
Ravi Kant AgrawalICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.
Mukesh SinghICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.
Indian Veterinary Research Institute · INCentral Avian Research Institute · INCentral Coastal Agricultural Research Institute · INCentral Institute for Research on Cattle · INDirectorate of Poultry Research · INIndian Council of Agricultural Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the rampant usage of antibiotics as growth promoters (AGPs) in poultry sector, there has been alarming concerns of antimicrobial resistant microbes such as Escherichia coli. Diversification of poultry farming due to consumer demand for safer products with higher protein content, turkey production is gaining popularity. Feed additives such as formic acid (FA) and thymol (TH) are effectively replacing AGPs due to their antimicrobial action. This directed the researchers to find alternatives to antibiotics such as thymol and formic acid because of their strong antimicrobial, anti-oxidative, digestive-stimulating properties. To assess the efficacy of FA and TH as growth promoters and their effect on the antimicrobial resistance (AMR) load, the current study (0-12 weeks) was conducted in CARI VIRAT turkey poults (n = 256; unsexed) those were randomly distributed into eight treatment groups: control(T1), AGP (T2), graded levels of FA (T3 to T5) @ 2.5, 5 and 7.5 ml/kg and TH (T6 to T8) @ 120, 240 and 350 mg/kg. Cloacal swab samples were collected at 0, 4th, 8th and 12th week interval and processed further for isolation, identification and assessment of resistance profile of E. coli. The final body weight, cumulative gain and FCR were significantly (p < 0.05) better for birds under supplementation. The Total plate count (TPC) and coliforms showcased a significant (p < 0.001) reduction in the FA and TH supplement groups as compared to control and AGP group. The resistance profile indicated E. coli isolates from AGP group with significantly (p < 0.001) highest resistivity against antibiotics (viz. chloramphenicol, tetracycline, nalidixic acid, chlortetracycline) while isolates from FA (T5) and TH (T8) groups were the least resistant. bla

Indexed as

Animal FeedDietary SupplementsEscherichia coliFormatesThymolTurkeysAnimalsDietDrug Resistance, BacterialEscherichia coli InfectionsPoultry DiseasesFormatesformic acidThymolAntimicrobial resistanceFormic acidThymolTurkey

Identifiers

PMID38539029
OpenAlexW4394751880

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.