Evidence map›Paper›PMID 38538928›Full record

ArticleBrain and behavior2024

Analysis of gait characteristics and related factors in patients with Parkinson's disease based on wearable devices.

Hongyin Tang, Xianglian Liao, Jian Yao, Yilan Xing, Xin Zhao, Weibin Cheng, Tianxiang Gu, Yan Huang, Guang Xu, Ping Luan and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Hongyin TangDepartment of Neurology, Guangdong Second Provincial General hospital, Guangzhou, Guangdong, China.ORCID 0009-0006-7745-7537
Xianglian LiaoDepartment of Neurology, Guangdong Second Provincial General hospital, Guangzhou, Guangdong, China.
Jian YaoDepartment of Neurology, Guangdong Second Provincial General hospital, Guangzhou, Guangdong, China.
Yilan XingDepartment of Neurology, Guangdong Second Provincial General hospital, Guangzhou, Guangdong, China.
Xin ZhaoDepartment of Neurology, Guangdong Second Provincial General hospital, Guangzhou, Guangdong, China.
Weibin ChengInstitute for Healthcare Artificial Intelligence Application, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Tianxiang GuDepartment of Neurology, Guangdong Second Provincial General hospital, Guangzhou, Guangdong, China.
Yan HuangDepartment of Neurology, Guangdong Second Provincial General hospital, Guangzhou, Guangdong, China.
Guang XuDepartment of Neurology, Guangdong Second Provincial General hospital, Guangzhou, Guangdong, China.
Ping LuanGuangdong Second Provincial General hospital, Alzheimer's Disease Clinical Research Center, Guangzhou, Guangdong, China.
Junzhang TianInstitute for Healthcare Artificial Intelligence Application, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Guihua LiDepartment of Neurology, Guangdong Second Provincial General hospital, Guangzhou, Guangdong, China.
Guangdong Provincial People's Hospital · CNShaanxi Research Association for Women and Family · CNShenzhen University · CN

Funding

National Key-Area Research and Development Program of China 2021YFC2009400Science and Technology Projects in Guangzhou 2024 Guangzhou School (Institute) Enterprise Joint Funding Project 2024A03J0924The key Project of Basic Research of Shenzhen JCYJ20200109113603854
6 · The paper itself

Abstract

backgroundPostural instability and gait disorder dominant (PIGD) is one of the most common disabling symptoms of Parkinson's disease (PD), which seriously affects patients' quality of life. Therefore, it is essential to identify PIGD and develop targeted interventions to reduce the risk of PIGD in PD patients.

aimThis study aimed to investigate the gait characteristics of PD patients based on wearable devices and to establish a predictive model for their related influencing factors.

methodsThe retrospective medical records of patients from January 2020 to September 2023 were collected, including 159 patients with PD (divided into PIGD [n = 73] and non-PIGD [n = 86] groups) and 200 healthy patients (as the healthy control group). Information from social demographic data, a blood test, scale scores, gait analysis based on wearable devices, white matter lesions, and the Fazekas scale was extracted and analyzed.

resultsCompared with the healthy control group, the mean step length, mean rate, mean angular velocity, and step length were lower in the PD group, while the mean steps were higher in the turning test. The incidence of PIGD was 46% in PD patients, and PD patients with the non-tremor onset mode were more likely to develop PIGD than those with the tremor onset mode. Compared to the non-PIGD group, the PIGD group showed more serious gait problems in different experimental tasks and had a higher Hoehn and Yahr (H-Y) stage, Hamilton Anxiety Scale (HAMA) score, Hamilton Depression Scale score, periventricular white matter (PVWM) score, deep white matter score, and Fazekas scale score, but they had lower hemoglobin levels, D-dimer levels, Tinetti Balance scores, Tinetti Gait scores, Berg Balance Scale scores, and Mini-Mental State Examination (MMSE) scores. Logistic regression analysis showed that the MMSE score was negatively correlated with the occurrence of PIGD, while the HAMA score, H-Y stage, PVWM score, and non-tremor form of onset were positively correlated with the occurrence of PIGD

conclusionThe incidence of gait disorder in PD patients is higher than that in the normal population. Moreover, cognitive dysfunction, anxiety state, H-Y stage, PVWM score, and the non-tremor mode of onset can be considered independent risk factors for PIGD.

Indexed as

Gait Disorders, NeurologicParkinson DiseaseWearable Electronic DevicesGaitHumansPostural BalanceQuality of LifeRetrospective StudiesTremorParkinson's diseasepostural instability and gait disorder dominant (PIGD)related factors

Identifiers

PMID38538928
PMCPMC10973098
OpenAlexW4393274876

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.