Evidence map›Paper›PMID 38538855›Full record

SynthesisEvidence-based dentistry2024

Antimicrobial efficacy of Odontopaste in endodontics: a systematic review.

Rachael Kendell-Wall, Jennifer-Thuy Nguyen, Fauve Salleras, Amandeep Singh Kamboj, Serene Aimee Diwen Tan, Vaidehi Manish Trivedi, João Martins de Mello-Neto, Rodrigo Rodrigues Amaral

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Evidence-based dentistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rachael Kendell-WallCollege of Medicine and Dentistry, James Cook University, Campus Smithfield, Cairns, QLD, Australia.
Jennifer-Thuy NguyenCollege of Medicine and Dentistry, James Cook University, Campus Smithfield, Cairns, QLD, Australia.
Fauve SallerasCollege of Medicine and Dentistry, James Cook University, Campus Smithfield, Cairns, QLD, Australia.
Amandeep Singh KambojCollege of Medicine and Dentistry, James Cook University, Campus Smithfield, Cairns, QLD, Australia.
Serene Aimee Diwen TanCollege of Medicine and Dentistry, James Cook University, Campus Smithfield, Cairns, QLD, Australia.
Vaidehi Manish TrivediCollege of Medicine and Dentistry, James Cook University, Campus Smithfield, Cairns, QLD, Australia.
João Martins de Mello-NetoCollege of Medicine and Dentistry, James Cook University, Campus Smithfield, Cairns, QLD, Australia.
Rodrigo Rodrigues AmaralCollege of Medicine and Dentistry, James Cook University, Campus Smithfield, Cairns, QLD, Australia. rodrigo.rodriguesamaral@jcu.edu.au.ORCID http://orcid.org/0000-0003-2473-5098
James Cook University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the efficacy of Odontopaste in reducing the microbial load in endodontics compared to other intracanal medicaments. MATERIALS AND

methodsThe literature was electronically searched on PubMed, Google Scholar, Scopus, Ovid Medline and Web of Science. In-vitro, ex-vivo and in-vivo studies that evaluated the antimicrobial efficacy of Odontopaste were included. The risk of bias was assessed using the Quality Assessment Tool for In Vitro Studies.

resultsA total of four in-vitro studies were included in the systematic review. One study showed that Odontopaste had significantly more microbial cell growth on roots in all dentine depths compared to other medicaments or test agents. Another study found that Odontopaste significantly decreased colony-forming units compared to propolis and chlorhexidine. Further results showed that Odontopaste did not significantly decrease microbial numbers when used in isolation. Additionally, combining Odontopaste and calcium hydroxide did not enhance the effectiveness of calcium hydroxide. The studies had a medium to high risk of bias.

conclusionThere is insufficient high-quality evidence to assess the antimicrobial efficacy of Odontopaste compared to other intracanal medicaments. Further research is required to determine Odontopaste's efficacy as an antimicrobial medicament in endodontics.

Indexed as

Root Canal IrrigantsAnti-Infective AgentsCalcium HydroxideEndodonticsHumansAnti-Infective AgentsCalcium HydroxideRoot Canal Irrigants

Identifiers

PMID38538855
PMCPMC11436364
OpenAlexW4393223503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.