Evidence map›Paper›PMID 38538145›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Visual Deprivation during Mouse Critical Period Reorganizes Network-Level Functional Connectivity.

Siyu Chen, Rachel M Rahn, Annie R Bice, Seana H Bice, Jonah A Padawer-Curry, Keith B Hengen, Joseph D Dougherty, Joseph P Culver

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Excitatory and inhibitory networks diverge following early blindness.Cerebral cortex (New York, N.Y. : 1991) · 2026
    Article
  2. Review
  3. Psychedelic 5-HTNature neuroscience · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Siyu ChenDepartments of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Rachel M RahnDepartments of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110.ORCID 0000-0002-9943-7573
Annie R BiceDepartments of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Seana H BiceDepartments of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Jonah A Padawer-CurryDepartments of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Keith B HengenBiology, Washington University School of Medicine, St. Louis, Missouri 63110.ORCID 0000-0001-5017-4090
Joseph D DoughertyGenetics, Washington University School of Medicine, St. Louis, Missouri 63110 jdougherty@wustl.edu culverj@wustl.edu.ORCID 0000-0002-6385-3997
Joseph P CulverDepartments of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110 jdougherty@wustl.edu culverj@wustl.edu.

Funding

WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JOSEPH D DOUGHERTY, Natasha Marrus · 2020 to 2026
$15.5M
High-Sensitivity DOT for Mapping Human Brain FunctionR01NS090874 · NINDS · WASHINGTON UNIVERSITY · PI CULVER, JOSEPH P · 2014 to 2025
$5.5M
Genomic and functional characterization of ASD and ID-associated MYT1L mutationR01MH124808 · NIMH · WASHINGTON UNIVERSITY · PI KROLL, KRISTEN L · 2021 to 2025
$3.7M
21ST CENTURY IMAGING SCIENCES: GRADUATE STUDENT TRAININGT32EB014855 · NIBIB · WASHINGTON UNIVERSITY · PI JOSEPH P CULVER, JOSEPH A O'SULLIVAN · 2012 to 2026
$3.1M
MAPPING FUNCTIONAL CONNECTIVITY WITH FLUORESCENCE MOLECULAR TOMOGRAPHYR01NS099429 · NINDS · WASHINGTON UNIVERSITY · PI CULVER, JOSEPH P · 2017 to 2021
$2.9M
REGULATION OF MAMMALIAN SOCIAL BEHAVIOR BY THE GTF2I FAMILY OF PROTEINSR01MH107515 · NIMH · WASHINGTON UNIVERSITY · PI DOUGHERTY, JOSEPH D · 2016 to 2020
$2.4M
Robust circuit computation in freely behaving animals.R01NS118442 · NINDS · WASHINGTON UNIVERSITY · PI HENGEN, KEITH B. · 2023 to 2024
$1.0M
NICHD NIH HHS P50 HD103525NIMH NIH HHS R01 MH107515NIMH NIH HHS R01 MH124808NINDS NIH HHS R01 NS090874NINDS NIH HHS R01 NS099429NINDS NIH HHS R01 NS118442
6 · The paper itself

Abstract

A classic example of experience-dependent plasticity is ocular dominance (OD) shift, in which the responsiveness of neurons in the visual cortex is profoundly altered following monocular deprivation (MD). It has been postulated that OD shifts also modify global neural networks, but such effects have never been demonstrated. Here, we use wide-field fluorescence optical imaging (WFOI) to characterize calcium-based resting-state functional connectivity during acute (3 d) MD in female and male mice with genetically encoded calcium indicators (

Indexed as

Mice, Inbred C57BLNerve NetSensory DeprivationVisual CortexAnimalsCritical Period, PsychologicalDominance, OcularFemaleMaleMiceNeuronal PlasticityVisual Pathwayscalcium neuroimagingcortical reorganizationfunctional connectivitymonocular deprivationplasticity

Identifiers

PMID38538145
PMCPMC11079959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.