Evidence map›Paper›PMID 38537949›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2024

Towards the adoption of quantitative computed tomography in the management of interstitial lung disease.

Simon L F Walsh, Jan De Backer, Helmut Prosch, Georg Langs, Lucio Calandriello, Vincent Cottin, Kevin K Brown, Yoshikazu Inoue, Vasilios Tzilas, Elizabeth Estes and 1 more

Abstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A systematic review of the role of quantitative CT in the prognostication and disease monitoring of interstitial lung disease.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Review
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  4. Review
  5. Article
  6. Article
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  13. Progressive pulmonary fibrosis: the importance of identification and intervention.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  14. Review
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  16. A Quantitative Imaging Measure of Progressive Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2025
    Article
  17. Article
  18. Article
  19. Imaging technologies in experimental pulmonary fibrosis research: essential tool for enhanced translational relevance.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Simon L F WalshNational Heart and Lung Institute, Imperial College, London, UK s.walsh@imperial.ac.uk.
Jan De BackerFLUIDDA, Antwerp, Belgium.
Helmut ProschMedical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-6119-6364
Georg LangsMedical University of Vienna, Vienna, Austria.
Lucio CalandrielloFondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Vincent CottinNational Reference Center for Rare Pulmonary Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, Claude Bernard University Lyon 1, UMR 754, Lyon, France.ORCID https://orcid.org/0000-0002-5591-0955
Kevin K BrownDepartment of Medicine, National Jewish Health, Denver, CO, USA.
Yoshikazu InoueClinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai City, Japan.ORCID https://orcid.org/0000-0003-3994-874X
Vasilios Tzilas5th Respiratory Department, Chest Diseases Hospital Sotiria, Athens, Greece.
Elizabeth EstesOpen Source Imaging Consortium (OSIC), Saugatuck, MI, USA.
Open Source Imaging Consortium (OSIC)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The shortcomings of qualitative visual assessment have led to the development of computer-based tools to characterise and quantify disease on high-resolution computed tomography (HRCT) in patients with interstitial lung diseases (ILDs). Quantitative CT (QCT) software enables quantification of patterns on HRCT with results that are objective, reproducible, sensitive to change and predictive of disease progression. Applications developed to provide a diagnosis or pattern classification are mainly based on artificial intelligence. Deep learning, which identifies patterns in high-dimensional data and maps them to segmentations or outcomes, can be used to identify the imaging patterns that most accurately predict disease progression. Optimisation of QCT software will require the implementation of protocol standards to generate data of sufficient quality for use in computerised applications and the identification of diagnostic, imaging and physiological features that are robustly associated with mortality for use as anchors in the development of algorithms. Consortia such as the Open Source Imaging Consortium have a key role to play in the collation of imaging and clinical data that can be used to identify digital imaging biomarkers that inform diagnosis, prognosis and response to therapy.

Indexed as

Artificial IntelligenceLung Diseases, InterstitialDisease ProgressionHumansLungPrognosisTomography, X-Ray Computed

Identifiers

PMID38537949
PMCPMC10966471

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.