Evidence map›Paper›PMID 38537270›Full record

Trial reportMedicine and science in sports and exercise2024

Plant Protein Blend Ingestion Stimulates Postexercise Myofibrillar Protein Synthesis Rates Equivalently to Whey in Resistance-Trained Adults.

Ino VAN DER Heijden, Alistair J Monteyne, Sam West, James P Morton, Carl Langan-Evans, Mark A Hearris, Doaa R Abdelrahman, Andrew J Murton, Francis B Stephens, Benjamin T Wall

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine and science in sports and exercise, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Ino VAN DER HeijdenDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, UNITED KINGDOM.
Alistair J MonteyneDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, UNITED KINGDOM.
Sam WestDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, UNITED KINGDOM.
James P MortonResearch Institute for Sport & Exercise Sciences, Liverpool John Moores University, Liverpool, UNITED KINGDOM.
Carl Langan-EvansResearch Institute for Sport & Exercise Sciences, Liverpool John Moores University, Liverpool, UNITED KINGDOM.
Mark A HearrisDepartment of Sport and Exercise Sciences, Institute of Sport, Manchester Metropolitan University, UNITED KINGDOM.
Doaa R Abdelrahman
Andrew J Murton
Francis B StephensDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, UNITED KINGDOM.
Benjamin T WallDepartment of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, UNITED KINGDOM.
Heavitree Hospital · GBHealth & Life (Taiwan) · TWLiverpool John Moores University · GBThe University of Texas Medical Branch at Galveston · USManchester Metropolitan University · GB

Funding

UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
NIA NIH HHS P30 AG024832
6 · The paper itself

Abstract

purposeWhey protein ingestion is typically considered an optimal dietary strategy to maximize myofibrillar protein synthesis (MyoPS) after resistance exercise. Although single-source plant protein ingestion is typically less effective, at least partly, due to less favorable amino acid profiles, this could theoretically be overcome by blending plant-based proteins with complementary amino acid profiles. We compared the postexercise MyoPS response after the ingestion of a novel plant-derived protein blend with an isonitrogenous bolus of whey protein.

methodsTen healthy, resistance-trained, young adults (male/female: 8/2; age: 26 ± 6 yr; BMI: 24 ± 3 kg·m -2 ) received a primed continuous infusion of L-[ ring - 2 H 5 ]-phenylalanine and completed a bout of bilateral leg resistance exercise before ingesting 32 g protein from whey (WHEY) or a plant protein blend (BLEND; 39.5% pea, 39.5% brown rice, 21.0% canola) in a randomized, double-blind crossover fashion. Blood and muscle samples were collected at rest, and 2 and 4 h after exercise and protein ingestion, to assess plasma amino acid concentrations, and postabsorptive and postexercise MyoPS rates.

resultsPlasma essential amino acid availability over the 4 h postprandial postexercise period was ~44% higher in WHEY compared with BLEND ( P = 0.04). From equivalent postabsorptive values (WHEY, 0.042 ± 0.020%·h -1 ; BLEND, 0.043 ± 0.015%·h -1 ) MyoPS rates increased after exercise and protein ingestion (time effect; P < 0.001) over a 0- to 2-h period (WHEY, 0.085 ± 0.037%·h -1 ; BLEND, 0.080 ± 0.037%·h -1 ) and 2- to 4-h period (WHEY, 0.085 ± 0.036%·h -1 ; BLEND, 0.086 ± 0.034%·h -1 ), with no differences between conditions during either period or throughout the entire (0-4 h) postprandial period (time-condition interactions; all P > 0.05).

conclusionsIngestion of a novel plant-based protein blend stimulates postexercise MyoPS to an equivalent extent as whey protein, demonstrating the utility of plant protein blends to optimize postexercise skeletal muscle reconditioning.

Indexed as

Cross-Over StudiesMuscle ProteinsMyofibrilsResistance TrainingWhey ProteinsAdultAmino AcidsDouble-Blind MethodFemaleHumansMaleMuscle, SkeletalOryzaPhenylalaninePlant ProteinsPostprandial PeriodAmino AcidsMuscle ProteinsPhenylalaninePlant ProteinsWhey Proteins

Identifiers

PMID38537270
PMCPMC11810040
OpenAlexW4393215715

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.