Evidence map›Paper›PMID 38536754›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Multi-axis fields boost SABRE hyperpolarization.

Jacob R Lindale, Loren L Smith, Mathew W Mammen, Shannon L Eriksson, Lucas M Everhart, Warren S Warren

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. High-resolution microtesla in-situJournal of magnetic resonance (San Diego, Calif. : 1997) · 2026
    Article
  5. Article
  6. Multidimensional pH-Temperature Mapping of SABRE-SHEATHThe journal of physical chemistry. B · 2025
    Article
  7. The journal of physical chemistry. B · 2025
    Article
  8. EfficientJournal of magnetic resonance open · 2025
    Article
  9. Scalable Hyperpolarized MRI Enabled by Ace-SABRE of [1-Angewandte Chemie (International ed. in English) · 2025
    Article
  10. Article
  11. Article
  12. Toward next-generation molecular imaging.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jacob R LindaleDepartment of Chemistry, Duke University, Durham, NC 27708.ORCID 0000-0001-7272-5375
Loren L SmithDepartment of Chemistry, Duke University, Durham, NC 27708.ORCID 0000-0003-3630-9213
Mathew W MammenDepartment of Physics, Duke University, Durham, NC 27708.ORCID 0009-0004-9321-0636
Shannon L ErikssonDepartment of Chemistry, Duke University, Durham, NC 27708.
Lucas M EverhartDepartment of Chemistry, Duke University, Durham, NC 27708.
Warren S WarrenDepartment of Chemistry, Duke University, Durham, NC 27708.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
National Science Foundation (NSF) CHE-2003109NIGMS NIH HHS T32 GM007171
6 · The paper itself

Abstract

The inherently low signal-to-noise ratio of NMR and MRI is now being addressed by hyperpolarization methods. For example, iridium-based catalysts that reversibly bind both parahydrogen and ligands in solution can hyperpolarize protons (SABRE) or heteronuclei (X-SABRE) on a wide variety of ligands, using a complex interplay of spin dynamics and chemical exchange processes, with common signal enhancements between 10

Indexed as

hyperpolarizationmagnetic resonanceoptimal control

Identifiers

PMID38536754
PMCPMC10998558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.