Evidence map›Paper›PMID 38536638›Full record

ArticleBiological trace element research2025

Sublethal Concentrations of Cadmium and Lead: Effects on Hemato-Biochemical Parameters and Tissue Accumulation in Wallagu attu.

Rim El Amouri, Javed Ahmed Ujan, Asif Raza, Alia Mushtaq, Muhammad Qamar Saeed, Samrah Masud, Syed Sikandar Habib, Marija Milošević, Salim S Al-Rejaie, Mohamed Mohany

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Article in Biological trace element research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rim El AmouriCollege of Fisheries and Life Sciences, Shanghai Ocean University, Shanghai, 201306, China.
Javed Ahmed UjanDepartment of Animal Sciences, University of Florida, Gainesville, FL, 32608, USA.
Asif RazaGovernment Degree College Nasirabad, District- Qambar-Shahdadkot, Sindh, 770020, Pakistan.
Alia MushtaqPlant and Environmental Protection, National Agricultural Research Centre, Islamabad, 45500, Pakistan.
Muhammad Qamar SaeedDepartment of Microbiology and Molecular Genetics, Bahauddin Zakariya University, Multan, 60800, Punjab, Pakistan.
Samrah MasudInstitute of Zoology, Bahauddin Zakariya University, Multan, 60800, Punjab, Pakistan.
Syed Sikandar HabibDepartment of Zoology, University of Sargodha, Sargodha, 40100, Punjab, Pakistan. sikandarzoo00@yahoo.com.
Marija MiloševićDepartment of Biology and Ecology, Faculty of Science, University of Kragujevac, Kragujevac, 34000, Serbia.
Salim S Al-RejaieDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 55760, Riyadh, 11451, Saudi Arabia.
Mohamed MohanyDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 55760, Riyadh, 11451, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The exposure of fish to heavy metals can significantly impact physiological processes and potentially lead to adverse health effects. This study assesses the effects of exposure to Cd and Pb sublethal concentrations in water on Wallagu attu. A total of 48 fish with an average body weight of 145.5 ± 26 g were distributed among three groups (control, Cd-treated, and Pb-treated) within 60 L fiberglass tanks. They were exposed to 30% sublethal concentrations of Cd and Pb for durations of 1, 15, and 30 days. Following this exposure, an assessment was conducted on metal bioaccumulation and hemato-biochemical responses. Results revealed a significantly (P < 0.05) higher concentration of heavy metals in the fish tissues of metals exposed groups than in the control. The concentration of Cd and Pb increases in fish tissues (kidney > gills > intestine) with exposure time. In most cases, the Pb-exposed group exhibited significantly (P < 0.05) higher concentrations of Pb in different tissues than the Cd-treated group. With extended exposure time, the activities of CAT and SOD show a significant decrease in both Cd and Pb-treated groups. However, the reduction in activities was more pronounced in the Cd-exposed group. On 15 and 30 days, the levels of red blood cells (RBC), hemoglobin (HB), hematocrit (HCT), and total protein (TP) decrease in groups exposed to Cd and Pb. The cortisol and glucose levels exhibit a more noticeable (P < 0.05) increase with prolonged exposure to Cd and Pb than the control group. On day 30, the survival rate decreased more in the Pb-exposed group. The findings of this study indicate that exposure to sublethal doses of Cd and Pb induces stress in Wallagu attu, resulting in rapid changes in specific hemato-biochemical parameters.

Indexed as

CadmiumLeadWater Pollutants, ChemicalAnimalsGillsSuperoxide DismutaseCadmiumLeadSuperoxide DismutaseWater Pollutants, ChemicalCadmiumHematologyLeadStressSublethal exposureWallagu attu

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.