Evidence map›Paper›PMID 38536503›Full record

ArticleWorld journal of urology2024

Vacuum-assisted mini-percutaneous nephrolithotomy is associated with lower rates of infectious complications compared to vacuum-cleaner procedure in patients at high risk for infections: a single-center experience.

Andrea Marmiroli, Marco Nizzardo, Stefano Paolo Zanetti, Gianpaolo Lucignani, Matteo Turetti, Carlo Silvani, Franco Gadda, Fabrizio Longo, Elisa De Lorenzis, Giancarlo Albo and 3 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Andrea MarmiroliDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Marco NizzardoDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Stefano Paolo ZanettiDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Gianpaolo LucignaniDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Matteo TurettiDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Carlo SilvaniDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Franco GaddaDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Fabrizio LongoDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Elisa De LorenzisDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Giancarlo AlboDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy. albo.giancarlo@gmail.com.ORCID http://orcid.org/0000-0003-1979-3437
Andrea SaloniaDivision of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, University Vita-Salute San Raffaele, Milan, Italy.
Emanuele MontanariDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Luca BoeriDepartment of Urology, Fondazione IRCCS Ca' GrandaOspedale Maggiore Policlinico, Milan, Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · ITIRCCS Ospedale San Raffaele · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the impact of vacuum-assisted mini-percutaneous nephrolithotomy (vamPCNL) vs. vacuum-cleaner mPCNL (vcmPCNL) on the rate of postoperative infectious complications in a cohort of patients with high risk factors for infections.

methodsWe retrospectively analysed data from 145 patients who underwent mPCNL between 01/2016 and 12/2022. Patient's demographics, stones characteristics and operative data were collected. vamPCNL and vcmPCNL were performed based on the surgeon's preference. High-risk patients were defied as having ≥ 2 predisposing factors for infections such as a history of previous urinary tract infections, positive urine culture before surgery, stone diameter ≥ 3 cm, diabetes mellitus and hydronephrosis. Complications were graded according to modified Clavien classification. Descriptive statistics and logistic regression models were used to identify factors associated with postoperative infectious complications.

resultsvamPCNL and vcmPCNL were performed in 94 (64.8%) and 51 (35.2%) cases, respectively. After surgery, infectious complications occurred in 43 (29.7%) participants. Patients who developed infectious complications had larger stone volume (p = 0.02) and higher rate of multiple stones (p = 0.01) than those who did not. Infectious complications occurred more frequently after vcmPCNL than vamPCNL (55.9% vs. 44.1%. p = 0.01) in high-risk patients. Longer operative time (p < 0.01) and length of stay (p < 0.01) were observed in cases with infectious complications. At multivariable logistic regression analysis, longer operative time (OR 1.1, p = 0.02) and vcmPCNL (OR 3.1, p = 0.03) procedures were independently associated with the risk of infectious complications post mPCNL, after accounting for stone volume.

conclusionOne out of three high-risk patients showed infectious complications after mPCNL. vamPCL and shorter operative time were independent protective factors for infections after surgery.

Indexed as

Kidney CalculiNephrolithotomy, PercutaneousUrinary Tract InfectionsHumansPostoperative ComplicationsRetrospective StudiesTreatment OutcomeAspirationInfectious complicationsPercutaneous nephrolithotomySafetyStone

Identifiers

PMID38536503
PMCPMC10973077
OpenAlexW4393233893

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.