Evidence map›Paper›PMID 38536445›Full record

ArticleMolecular biology of the cell2024

After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells.

Ivy S Han, Junmin Hua, James S White, James T O'Connor, Lila S Nassar, Kaden J Tro, Andrea Page-McCaw, M Shane Hutson

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ivy S HanDepartment of Cell & Developmental Biology, Vanderbilt University, Nashville, TN 37240.
Junmin HuaDepartment of Cell & Developmental Biology, Vanderbilt University, Nashville, TN 37240.
James S WhiteDepartment of Cell & Developmental Biology, Vanderbilt University, Nashville, TN 37240.
James T O'ConnorDepartment of Cell & Developmental Biology, Vanderbilt University, Nashville, TN 37240.
Lila S NassarDepartment of Physics & Astronomy, Vanderbilt University, Nashville, TN 37240.
Kaden J TroDepartment of Physics & Astronomy, Vanderbilt University, Nashville, TN 37240.
Andrea Page-McCawDepartment of Cell & Developmental Biology, Vanderbilt University, Nashville, TN 37240.
M Shane HutsonDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37240.ORCID 0000-0002-1647-6092
Vanderbilt University · US

Funding

Training Program in Stem Cell and Regenerative Developmental BiologyT32HD007502 · NICHD · VANDERBILT UNIVERSITY · PI WRIGHT, CHRISTOPHER V · 1997 to 2022
$5.4M
Cellular Integration of Information in the Detection and Response to Epithelial DamageR01GM130130 · NIGMS · VANDERBILT UNIVERSITY · PI HUTSON, M. SHANE, PAGE-MCCAW, ANDREA · 2018 to 2025
$2.9M
NICHD NIH HHS T32 HD007502NIGMS NIH HHS R01 GM130130
6 · The paper itself

Abstract

The maintenance of epithelial barrier function involves cellular tension, with cells pulling on their neighbors to maintain epithelial integrity. Wounding interrupts cellular tension, which may serve as an early signal to initiate epithelial repair. To characterize how wounds alter cellular tension we used a laser-recoil assay to map cortical tension around wounds in the epithelial monolayer of the

Indexed as

Epithelial CellsWound HealingAnimalsDrosophilaReceptors, G-Protein-CoupledSignal TransductionReceptors, G-Protein-Coupled

Identifiers

PMID38536445
PMCPMC11151093
OpenAlexW4393220151

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.