Evidence map›Paper›PMID 38536408›Full record

ArticleACS synthetic biology2024

Building Synthetic Biosensors Using Red Blood Cell Proteins.

Taylor B Dolberg, Taylor F Gunnels, Te Ling, Kelly A Sarnese, John D Crispino, Joshua N Leonard

Abstract read
In one paragraph

Article in ACS synthetic biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Taylor B DolbergDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States.
Taylor F GunnelsCenter for Synthetic Biology, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-2498-2630
Te LingDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, TN 38105-3678, United States.
Kelly A SarneseDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States.
John D CrispinoDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, TN 38105-3678, United States.ORCID 0000-0002-8182-8306
Joshua N LeonardDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0003-4359-6126

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
Developing Capacity to Evaluate Training Programs via Development of Human, Institutional and Social CapitalT32GM008449 · NIGMS · NORTHWESTERN UNIVERSITY · PI LEONARD, JOSHUA NATHANIEL · 1993 to 2023
$7.8M
Design-driven engineering of robust mammalian sense-and-respond functions: from parts to programsR01EB026510 · NIBIB · NORTHWESTERN UNIVERSITY · PI Neda Bagheri, Joshua Nathaniel Leonard · 2018 to 2026
$3.7M
NCI NIH HHS P30 CA060553NIBIB NIH HHS R01 EB026510NIGMS NIH HHS T32 GM008449
6 · The paper itself

Abstract

As the use of engineered cell therapies expands from pioneering efforts in cancer immunotherapy to other applications, an attractive but less explored approach is the use of engineered red blood cells (RBCs). Compared to other cells, RBCs have a very long circulation time and reside in the blood compartment, so they could be ideally suited for applications as sentinel cells that enable

Indexed as

Biosensing TechniquesErythrocytesLigandsMembrane ProteinsLigandsMembrane ProteinsbiosensorGPAKellred blood cellsynthetic receptor

Identifiers

PMID38536408
PMCPMC11536268

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.