Evidence map›Paper›PMID 38536011›Full record

ArticleEuropean journal of translational myology2024

Evaluation of diagnostic value of Doppler ultrasound in the diagnosis of malignant breast masses.

Bahareh Mehdikhani, Milad Benam, Afrooz Moradkhani, Ayda Roostaee, Seyedeh Sabahat Bahman, Pooyan Barmayoon, Ghazaleh Dezyani, Zeinab Safarpour Lima

Open access · goldAbstract read
In one paragraph

Article in European journal of translational myology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bahareh MehdikhaniDepartment of Radiology, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran. bahare.mehdikhani@gmail.com.
Milad BenamDepartment of Radiology, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran. miladbenam.md@gmail.com.
Afrooz MoradkhaniDezful University of Medical Sciences, Dezful. afroozmoradkhani@gmail.com.
Ayda RoostaeeDepartment of Radiology, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran. ayda152001@yahoo.com.
Seyedeh Sabahat BahmanDepartment of Radiology, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran. sabahat88.b@gmail.com.
Pooyan BarmayoonDepartment of Radiology, Firoozgar Clinical Research Development Center (FCRDC), Iran University of Medical Sciences, Tehran. pooyan.b808@gmail.com.
Ghazaleh DezyaniDepartment of Radiology, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran. dezyanighazal@gmail.com.
Zeinab Safarpour LimaDepartment of Radiology, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran. drsafarpourlima@gmail.com.
Iran University of Medical Sciences · IRDezful University of Medical Sciences · IRFiroozgar General Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the leading cause of cancer mortality in women, and it is on the rise in Iran. Therefore, an early-stage diagnosis of breast cancer is of critical importance. Because ultrasound is one of the available, inexpensive, and minimally invasive techniques for distinguishing malignant from benign masses, a comparison of conventional ultrasound, color Doppler, and spectral Doppler findings can be useful. The purpose of this study was to determine the diagnostic value of sonographic indices, specifically Doppler parameters, in identifying the nature of breast masses. This is a cross-sectional study, with diagnostic value analysis. Before undergoing a biopsy, 80 patients with breast masses underwent B-mode and Doppler breast ultrasound. The ultrasound findings were then compared to pathologic results to determine which groups were malignant or benign. The resulting data were analyzed using statistical tests and diagnostic values with SPSS 22 software. B-mode grey-scale ultrasound indices such as mass shape, mass margin, mass orientation, and posterior features, as well as Doppler indices such as vascularity, RI (Resistive Index), PI (Pulsatility Index), and PSV (Peak Systolic Velocity), were found to be statistically significant with pathological findings. Color Doppler revealed vascularity in 65% of benign and 84% of malignant masses. The diagnostic value results revealed that mass shape, mass margin, mass orientation, and posterior features all play a significant role in predicting lesion malignancy, with a sensitivity of 92%, 58%, 64%, 56%, and specificity of 59%, 66%, 82%, and 84%, respectively. The RI, PI, and PSV indices were significantly higher in malignant masses, and all of them had remarkable diagnostic values in predicting malignancy, with a (Area Under The Curve) AUC of 0.863, 0.882, 0.702, a sensitivity of 84% and 84%, 68%, and a specificity of 83%, 86%, and 62%, respectively, at the optimal cut-off points (0.65, 1.32, 12.40) obtained from the Receiver Operating Characteristics (ROC) curves.

Identifiers

PMID38536011
PMCPMC11264213
OpenAlexW4393189436

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.