Evidence map›Paper›PMID 38535830›Full record

ArticleThe Analyst2024

Spatially resolved quantification of oxygen consumption rate in

Parastoo Anbaei, Marissa G Stevens, Alexander G Ball, Timothy N J Bullock, Rebecca R Pompano

Abstract read
In one paragraph

Article in The Analyst, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Parastoo AnbaeiDepartment of Chemistry, University of Virginia College of Arts and, Sciences, Charlottesville, Virginia 22904, USA. rpompano@virginia.edu.
Marissa G StevensDepartment of Pathology, University of Virginia, Charlottesville, Virginia 22903, USA.
Alexander G BallDepartment of Microbiology Cancer Biology and Immunology, University of Virginia, Charlottesville, Virginia 22903, USA.
Timothy N J BullockDepartment of Pathology, University of Virginia, Charlottesville, Virginia 22903, USA.
Rebecca R PompanoDepartment of Chemistry, University of Virginia College of Arts and, Sciences, Charlottesville, Virginia 22904, USA. rpompano@virginia.edu.ORCID http://orcid.org/0000-0002-8644-9313

Funding

Modeling immunity with a hybrid lymph node tissue-chipR01AI131723 · NIAID · UNIVERSITY OF VIRGINIA · PI POMPANO, REBECCA R · 2018 to 2022
$2.3M
Towards GLIMPSE: Enabling technology to map cytokines in inflamed tissueR21AI160547 · NIAID · UNIVERSITY OF VIRGINIA · PI KELLY, KIMBERLY A., POMPANO, REBECCA R · 2021 to 2022
$410k
NIAID NIH HHS R01 AI131723NIAID NIH HHS R21 AI160547
6 · The paper itself

Abstract

Cellular metabolism has been closely linked to activation state in cells of the immune system, and the oxygen consumption rate (OCR) in particular serves as a valuable metric for assessing metabolic activity. Several oxygen sensing assays have been reported for cells in standard culture conditions. However, none have provided a spatially resolved, optical measurement of local oxygen consumption in intact tissue samples, making it challenging to understand regional dynamics of consumption. Therefore, here we established a system to monitor the rates of oxygen consumption in

Indexed as

Lymph NodesOxygen ConsumptionAnimalsMiceMice, Inbred C57BLOxygenT-LymphocytesOxygen

Identifiers

PMID38535830
PMCPMC11056769

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.