Evidence map›Paper›PMID 38535735›Full record

ArticleSports (Basel, Switzerland)2024

Metabolomic and Proteomic Profiling of Athletes Performing Physical Activity under Hypoxic Conditions.

Kristina A Malsagova, Arthur T Kopylov, Alexander A Stepanov, Liudmila I Kulikova, Alexander A Izotov, Ksenia A Yurku, Evgenii I Balakin, Vasiliy I Pustovoyt, Anna L Kaysheva

Open access · goldAbstract read
In one paragraph

Article in Sports (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kristina A MalsagovaInstitute of Biomedical Chemistry, 119121 Moscow, Russia.ORCID 0000-0001-9404-1660
Arthur T KopylovInstitute of Biomedical Chemistry, 119121 Moscow, Russia.ORCID 0000-0002-7199-372X
Alexander A StepanovInstitute of Biomedical Chemistry, 119121 Moscow, Russia.ORCID 0000-0002-9113-9440
Liudmila I KulikovaInstitute of Biomedical Chemistry, 119121 Moscow, Russia.
Alexander A IzotovInstitute of Biomedical Chemistry, 119121 Moscow, Russia.
Ksenia A YurkuState Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 119435 Moscow, Russia.
Evgenii I BalakinState Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0001-5545-135X
Vasiliy I PustovoytState Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 119435 Moscow, Russia.
Anna L KayshevaInstitute of Biomedical Chemistry, 119121 Moscow, Russia.ORCID 0000-0003-4472-2016
Institute of Biomedical Chemistry · RUState Scientific Center of the Russian Federation - Federal Medical Biophysical Center named after A.I. Burnazyan · RU

Funding

the Ministry of Science and Higher Education of the Russian Federation 75-15-2022-305
6 · The paper itself

Abstract

Proteomic and metabolomic research enables quantitation of the molecular profile of athletes. Multiomic profiling was conducted using plasma samples collected from 18 male athletes performing aerobic activity (running) at high altitude. Metabolomic profiling detected changes in the levels of 4-hydroxyproline, methionine, oxaloacetate, and tyrosine during the recovery period. Furthermore, proteomic profiling revealed changes in expression of proteins contributing to the function of the immune system, muscle damage, metabolic fitness and performance, as well as hemostasis. Further research should focus on developing metabolic models to monitor training intensity and athlete adaptation.

Indexed as

athletesmass spectrometry analysismetabolomemolecular profileproteome

Identifiers

PMID38535735
PMCPMC10975304
OpenAlexW4392461538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.