Evidence map›Paper›PMID 38535545›Full record

ArticlePathogens (Basel, Switzerland)2024

Resurgence of Dengue Virus Serotype 3 in Minas Gerais, Brazil: A Case Report.

Talita Adelino, Maurício Lima, Natália R Guimarães, Joilson Xavier, Vagner Fonseca, Luiz Marcelo R Tomé, Maira Alves Pereira, Vanessa Ferreira Machado, Luiz Carlos Junior Alcantara, Felipe C de Melo Iani and 1 more

Abstract readCase Reports
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Tracing Dengue's Evolutionary and Phylogenetic Pathways.Current topics in microbiology and immunology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Talita AdelinoFundação Ezequiel Dias, Belo Horizonte 30510-010, Brazil.
Maurício LimaFundação Ezequiel Dias, Belo Horizonte 30510-010, Brazil.
Natália R GuimarãesFundação Ezequiel Dias, Belo Horizonte 30510-010, Brazil.ORCID 0000-0002-9859-5895
Joilson XavierInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte 30190-009, Brazil.
Vagner FonsecaDepartment of Exact and Earth Science, University of the State of Bahia, Salvador 41192-010, Brazil.ORCID 0000-0001-5521-6448
Luiz Marcelo R ToméFundação Ezequiel Dias, Belo Horizonte 30510-010, Brazil.ORCID 0000-0002-1477-5558
Maira Alves PereiraFundação Ezequiel Dias, Belo Horizonte 30510-010, Brazil.
Vanessa Ferreira MachadoSecretaria Municipal de Saúde de Belo Horizonte, Belo Horizonte 30130-012, Brazil.
Luiz Carlos Junior AlcantaraInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte 30190-009, Brazil.ORCID 0000-0002-6769-9931
Felipe C de Melo IaniFundação Ezequiel Dias, Belo Horizonte 30510-010, Brazil.
Marta GiovanettiInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte 30190-009, Brazil.ORCID 0000-0002-5849-7326

Funding

University of Washington Arboviral Research Network (UWARN)U01AI151698 · NIAID · UNIVERSITY OF WASHINGTON · PI Michael Gale, PETER MACGARR RABINOWITZ · 2020 to 2026
$13.3M
NIAID NIH HHS U01 AI151698NIH HHS U01 AI151698
6 · The paper itself

Abstract

This report provides a detailed overview of the resurgence of DENV-3 in the state of Minas Gerais, Brazil, which is a concerning scenario in the context of dengue, a mosquito-borne viral disease. Historically, Brazil has grappled with dengue epidemics caused primarily by the DENV-1 and DENV-2 serotypes. However, in 2023, a significant shift in this pattern was observed as DENV-3 made a notable resurgence. This resurgence was characterized by the increase in DENV-3 cases within the country and the region of the Americas. Given the absence of sustained DENV-3 circulation in Brazil in previous years, this situation poses a significant risk, making the population highly susceptible to a potential novel epidemic. In November 2023, a 31-year-old male patient in Belo Horizonte exhibited symptoms of acute febrile syndrome. Multiplex RT-qPCR using the Kit Molecular ZC D-Tipagem confirmed DENV-3 infection, suggesting a likely autochthonous case, as the patient reported no travel history. To promptly assess this resurgence, we applied the nanopore sequencing technology. This allowed for the rapid characterization of the initial DENV-3 case isolated in Minas Gerais in 2023, representing a 13-year interval since the serotype's previous documented circulation in that state. This case report underscores the critical importance of proactive monitoring and the swift implementation of targeted control strategies to address the evolving dynamics of dengue, with a specific emphasis on the resurgence of DENV-3 in the state.

Indexed as

DengueDengue VirusSerogroupAdultBrazilHumansMalePhylogenyDENV monitoringmolecular epidemiologynext-generation sequencing

Identifiers

PMID38535545
PMCPMC10974589

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.