Evidence map›Paper›PMID 38535540›Full record

ReviewPathogens (Basel, Switzerland)2024

Types and Mechanisms of Efflux Pump Systems and the Potential of Efflux Pump Inhibitors in the Restoration of Antimicrobial Susceptibility, with a Special Reference to

Kira M Zack, Trent Sorenson, Suresh G Joshi

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Review
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  11. TXA11114: Discovery of anAntibiotics (Basel, Switzerland) · 2026
    Article
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  14. Microbial Biofilms Dynamics and Functionality in an UrbanEnvironmental science & technology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kira M ZackCenter for Surgical Infections and Biofilms, Department of Surgery, College of Medicine, Drexel University, Philadelphia, PA 19104, USA.
Trent SorensonCenter for Surgical Infections and Biofilms, Drexel School of Biomedical Engineering, Science & Health Systems, Drexel University, Philadelphia, PA 19104, USA.
Suresh G JoshiCenter for Surgical Infections and Biofilms, Department of Surgery, College of Medicine, Drexel University, Philadelphia, PA 19104, USA.ORCID 0000-0002-7838-4898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria express a plethora of efflux pumps that can transport structurally varied molecules, including antimicrobial agents and antibiotics, out of cells. Thus, efflux pump systems participate in lowering intracellular concentrations of antibiotics, which allows phenotypic multidrug-resistant (MDR) bacteria to survive effectively amid higher concentrations of antibiotics.

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsDrug Resistance, Multiple, BacterialMembrane Transport ProteinsAcinetobacter InfectionsHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsAcinetobacter baumanniiantibioticscarbapenem resistanceCRABefflux pumpefflux pump inhibitorsEPIMDRmultidrug resistancenosocomial infectiontransferable antimicrobial resistance

Identifiers

PMID38535540
PMCPMC10974122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.