Evidence map›Paper›PMID 38535538›Full record

ArticlePathogens (Basel, Switzerland)2024

Oral Microbiome Stamp in Alzheimer's Disease.

Argul Issilbayeva, Aiym Kaiyrlykyzy, Elizaveta Vinogradova, Zharkyn Jarmukhanov, Samat Kozhakhmetov, Aliya Kassenova, Madiyar Nurgaziyev, Nurislam Mukhanbetzhanov, Dinara Alzhanova, Gulnaz Zholdasbekova and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Argul IssilbayevaCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.ORCID 0000-0002-7350-6083
Aiym KaiyrlykyzyCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.
Elizaveta VinogradovaCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.
Zharkyn JarmukhanovCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.
Samat KozhakhmetovCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.ORCID 0000-0001-9668-0327
Aliya KassenovaCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.ORCID 0000-0002-3670-3600
Madiyar NurgaziyevCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.
Nurislam MukhanbetzhanovCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.
Dinara AlzhanovaDepartment of Neurology, Medical University Astana, Astana Z05H0P9, Kazakhstan.
Gulnaz ZholdasbekovaCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.
Sholpan AskarovaCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.ORCID 0000-0001-6161-1671
Almagul R KushugulovaCenter for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana Z05H0P9, Kazakhstan.ORCID 0000-0001-9479-0899
Nazarbayev University · KZAstana Medical University · KZKaraganda Medical University · KZNational Research Center for Maternal and Child Health · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have suggested that periodontal disease and alterations in the oral microbiome may be associated with cognitive decline and Alzheimer's disease (AD) development. Here, we report a case-control study of oral microbiota diversity in AD patients compared to healthy seniors from Central Asia. We have characterized the bacterial taxonomic composition of the oral microbiome from AD patients (n = 64) compared to the healthy group (n = 71) using 16S ribosomal RNA sequencing. According to our results, the oral microbiome of AD has a higher microbial diversity, with an increase in

Indexed as

Alzheimer DiseaseMicrobiotaMouthRNA, Ribosomal, 16SAgedAged, 80 and overBacteriaCase-Control StudiesFemaleHumansMalePeriodontitisRNA, Ribosomal, 16S16S rRNAAlzheimer’s diseaseKazakhstan populationmetabolic pathwaysmicrobiomeoral cavitysequencing

Identifiers

PMID38535538
PMCPMC10975384
OpenAlexW4392110319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.