Evidence map›Paper›PMID 38535480›Full record

ArticleMarine drugs2024

Purification of an Acidic Polysaccharide with Anticoagulant Activity from the Marine Sponge

Gabriele Nieddu, Gabriele Obino, Cristina Ciampelli, Antonio Brunetti, Tiziana Cubeddu, Renata Manconi, Giacinta Angela Stocchino, Giovanni Andrea Deiana, Marilena Formato, Antonio Junior Lepedda

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Gabriele NiedduDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.ORCID 0000-0002-9268-9436
Gabriele ObinoDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.ORCID 0000-0002-3192-755X
Cristina CiampelliDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.ORCID 0000-0002-1761-3124
Antonio BrunettiDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.
Tiziana CubedduDepartment of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.ORCID 0000-0001-7522-8200
Renata ManconiDepartment of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.ORCID 0000-0003-0544-4105
Giacinta Angela StocchinoDepartment of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
Giovanni Andrea DeianaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.
Marilena FormatoDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.ORCID 0000-0001-9207-5787
Antonio Junior LepeddaDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43b, 07100 Sassari, Italy.ORCID 0000-0002-8356-894X
University of Sassari · IT

Funding

European Union PROGETTI DI RICERCA INTERDISCIPLINARE - DM 737/2021, RISORSE 2021 - 2022, Finanziato dall'Unione europea - NextGenerationEUFondazione di Sardegna BANDO FONDAZIONE DI SARDEGNA 2022 E 2023-PROGETTI DI RICERCA DI BASE DI-PARTIMENTALI (D.R.16/2022)
6 · The paper itself

Abstract

Thromboembolic conditions are the most common cause of death in developed countries. Anticoagulant therapy is the treatment of choice, and heparinoids and warfarin are the most adopted drugs. Sulphated polysaccharides extracted from marine organisms have been demonstrated to be effective alternatives, blocking thrombus formation by inhibiting some factors involved in the coagulation cascade. In this study, four acidic glycan fractions from the marine sponge

Indexed as

PoriferaAnimalsAnticoagulantsBlood CoagulationGlycosaminoglycansHumansPolysaccharidesSulfatesAnticoagulantsGlycosaminoglycansPolysaccharidesSulfatesanticoagulant activityfucosylated chondroitin sulphatemarine invertebratesPoriferasustainable sponge culture

Identifiers

PMID38535480
PMCPMC10971851
OpenAlexW4393043807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.