Evidence map›Paper›PMID 38535140›Full record

ArticleJournal of imaging2024

Development of A Micro-CT Scanner with Dual-Energy Option and Endovascular Contrast Agent Administration Protocol for Fetal and Neonatal Virtual Autopsy.

Robert Zboray, Wolf Schweitzer, Lars Ebert, Martin Wolf, Sabino Guglielmini, Stefan Haemmerle, Stephan Weiss, Bruno Koller

Open access · goldAbstract read
In one paragraph

Article in Journal of imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Robert ZborayCenter for X-ray Analytics, Empa-Swiss Federal Laboratories for Materials Science and Technology, 8600 Dübendorf, Switzerland.ORCID 0000-0003-0811-7396
Wolf SchweitzerZurich Institute of Forensic Medicine, University of Zurich, 8057 Zurich, Switzerland.
Lars EbertDepartments of the Zurich Forensic Science Institute, Forensisches Institut Zürich, 8010 Zurich, Switzerland.
Martin WolfDepartment for Neonatology, University Hospital Zürich, 8091 Zurich, Switzerland.
Sabino GuglielminiDepartment for Neonatology, University Hospital Zürich, 8091 Zurich, Switzerland.ORCID 0000-0001-6493-2753
Stefan HaemmerleSCANCO Medical AG, 8306 Brüttisellen, Switzerland.
Stephan WeissSCANCO Medical AG, 8306 Brüttisellen, Switzerland.
Bruno KollerSCANCO Medical AG, 8306 Brüttisellen, Switzerland.
Scanco Medical (Switzerland) · CHUniversity Hospital of Zurich · CHSwiss Federal Laboratories for Materials Science and Technology · CHUniversity of Zurich · CH

Funding

Innosuisse - Swiss Innovation Agency 28314.1PFLS-LS-1.
6 · The paper itself

Abstract

The rate of parental consent for fetal and perinatal autopsy is decreasing, whereas parents are more likely to agree to virtual autopsy by non-invasive imaging methods. Fetal and perinatal virtual autopsy needs high-resolution and good soft-tissue contrast for investigation of the cause of death and underlying trauma or pathology in fetuses and stillborn infants. This is offered by micro-computed tomography (CT), as opposed to the limited resolution provided by clinical CT scanners, and this is one of the most promising tools for non-invasive perinatal postmortem imaging. We developed and optimized a micro-CT scanner with a dual-energy imaging option. It is dedicated to post-mortem CT angiography and virtual autopsy of fetuses and stillborn infants in that the chamber can be cooled down to around 5 °C; this increases tissue rigidity and slows decomposition of the native specimen. This, together with the dedicated gantry-based architecture, attempts to reduce potential motion artifacts. The developed methodology is based on prior endovascular injection of a BaSO

Indexed as

dual-energy CTfetal postmortem imagingmicro-CTPMCTAvirtual autopsy

Identifiers

PMID38535140
PMCPMC10971097
OpenAlexW4392296209

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.