Evidence map›Paper›PMID 38535033›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Pulmonary Adverse Events in Cancer Immunotherapy: Case Studies of CT Patterns.

Giorgio Bocchini, Maria Chiara Imperato, Tullio Valente, Salvatore Guarino, Roberta Lieto, Candida Massimo, Emanuele Muto, Federica Romano, Mariano Scaglione, Giacomo Sica and 4 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Giorgio BocchiniDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.
Maria Chiara ImperatoDepartment of Radiology, S. M. I. dell'Olmo Hospital, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D'Aragona, 84013 Cava de' Tirreni, Italy.ORCID 0000-0003-4362-8685
Tullio ValenteDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.ORCID 0000-0002-8799-0398
Salvatore GuarinoDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.ORCID 0000-0003-3978-2567
Roberta LietoDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.
Candida MassimoDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.
Emanuele MutoDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.
Federica RomanoDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.
Mariano ScaglioneRadiology Department of Surgery, Medicine and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-0910-8064
Giacomo SicaDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.ORCID 0000-0002-9518-9744
Davide Vitagliano TorreDepartment of Radiology, S. Francesco D'Assisi Hospital, 84020 Oliveto Citra, Italy.ORCID 0000-0002-4596-4159
Salvatore MasalaRadiology Department of Surgery, Medicine and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Marialuisa BocchinoDepartment of Clinical Medicine and Surgery, Section of Respiratory Diseases, University Federico II, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.
Gaetano ReaDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, Italy.ORCID 0000-0002-5846-7872
Ospedale Monaldi · ITUniversity of Sassari · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune-checkpoint inhibitors have profoundly changed cancer treatment, improving the prognosis of many oncologic patients. However, despite the good efficacy of these drugs, their mechanism of action, which involves the activation of the immune system, can lead to immune-related adverse events, which may affect almost all organs. Pulmonary adverse events are relatively common, and potentially life-threatening complications may occur. The diagnosis is challenging due to the wide and non-specific spectrum of clinical and radiological manifestations. The role of the radiologist is to recognize and diagnose pulmonary immune-related adverse events, possibly even in the early stages, to estimate their extent and guide patients' management.

Indexed as

hypersensitivity pneumonitisimmune-checkpoint inhibitorsimmune-related adverse eventslung toxicitynon-specific interstitial pneumoniaorganizing pneumoniasarcoid-like reaction

Identifiers

PMID38535033
PMCPMC10969105
OpenAlexW4392817098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.