Evidence map›Paper›PMID 38534949›Full record

ArticleCurrent oncology (Toronto, Ont.)2024

Wedge Resection versus Stereotactic Body Radiation Therapy for Non-Small Cell Lung Cancer Tumors ≤8 mm.

Arian Mansur, Zain Saleem, Jorind Beqari, Camille Mathey-Andrews, Alexandra L Potter, James Cranor, Alexandra T Nees, Deepti Srinivasan, Margaret E Yang, Chi-Fu Jeffrey Yang and 1 more

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Arian MansurDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0003-2406-5127
Zain SaleemDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Jorind BeqariDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Camille Mathey-AndrewsDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Alexandra L PotterDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
James CranorDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Alexandra T NeesDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Deepti SrinivasanDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0002-0730-6841
Margaret E YangDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0009-0005-8472-9855
Chi-Fu Jeffrey YangDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Hugh G AuchinclossDivision of Thoracic Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to evaluate the overall survival of patients with ≤8 mm non-small cell lung cancer (NSCLC) who undergo wedge resection versus stereotactic body radiation therapy (SBRT). Kaplan-Meier analysis, multivariable Cox proportional hazards modeling, and propensity score-matched analysis were performed to evaluate the overall survival of patients with ≤8 mm NSCLC in the National Cancer Database (NCDB) from 2004 to 2017 who underwent wedge resection versus patients who underwent SBRT. The above-mentioned matched analyses were repeated for patients with no comorbidities. Patients who were coded in the NCDB as having undergone radiation because surgery was contraindicated due to patient risk factors (e.g., comorbid conditions, advance age, etc.) and those with a history of prior malignancy were excluded from analysis. Of the 1505 patients who had NSCLC ≤8 mm during the study period, 1339 (89%) patients underwent wedge resection, and 166 (11%) patients underwent SBRT. In the unadjusted analysis, multivariable Cox modeling and propensity score-matched analysis, wedge resection was associated with improved survival when compared to SBRT. These results were consistent in a sensitivity analysis limited to patients with no comorbidities.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsRadiosurgeryComorbidityHumansKaplan-Meier Estimatelung cancerNSCLCscreeningstereotactic body radiation therapywedge resection

Identifiers

PMID38534949
PMCPMC10969215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.