Evidence map›Paper›PMID 38534726›Full record

ArticleCurrent issues in molecular biology2024

Protective Effect of Vitamin K2 (MK-7) on Acute Lung Injury Induced by Lipopolysaccharide in Mice.

Weidong Yang, Yulian Wang, Lulu Liu, Lihong Liu, Shuzhuang Li, Yuyuan Li

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Weidong YangCollege of Basic Medical Science, Dalian Medical University, Dalian 116041, China.
Yulian WangCollege of Basic Medical Science, Dalian Medical University, Dalian 116041, China.
Lulu LiuCollege of Basic Medical Science, Dalian Medical University, Dalian 116041, China.
Lihong LiuCollege of Basic Medical Science, Dalian Medical University, Dalian 116041, China.
Shuzhuang LiCollege of Basic Medical Science, Dalian Medical University, Dalian 116041, China.
Yuyuan LiAdvanced Institute for Medical Sciences, Dalian Medical University, Dalian 116041, China.
Dalian Medical University · CN

Funding

China Health Promotion Association Z093001General Project of Liaoning Provincial Department of Education JYTMS20230566
6 · The paper itself

Abstract

Vitamin K2 (MK-7) has been shown to cause significant changes in different physiological processes and diseases, but its role in acute lung injury (ALI) is unclear. Therefore, in this study, we aimed to evaluate the protective effects of VK2 against LPS-induced ALI in mice. The male C57BL/6J mice were randomly divided into six groups (n = 7): the control group, LPS group, negative control group (LPS + Oil), positive control group (LPS + DEX), LPS + VK2 (L) group (VK2, 1.5 mg/kg), and LPS + VK2 (H) group (VK2, 15 mg/kg). Hematoxylin-eosin (HE) staining of lung tissue was performed. Antioxidant superoxide dismutase (SOD) and total antioxidant capacity (T-AOC) activities, and the Ca

Indexed as

acute lung injuryapoptosisautophagymitochondrial damagetight junction injuryvitamin K2

Identifiers

PMID38534726
PMCPMC10968901
OpenAlexW4392110963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.