Evidence map›Paper›PMID 38534718›Full record

ArticleAntibiotics (Basel, Switzerland)2024

One Hundred Explicit Definitions of Potentially Inappropriate Prescriptions of Antibiotics in Hospitalized Older Patients: The Results of an Expert Consensus Study.

Nicolas Baclet, Emmanuel Forestier, Gaëtan Gavazzi, Claire Roubaud-Baudron, Vincent Hiernard, Rozenn Hequette-Ruz, Serge Alfandari, Hugues Aumaître, Elisabeth Botelho-Nevers, Pauline Caraux-Paz and 12 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 18 institutions in 2 countries.

Nicolas BacletCHU Lille, University of Lille, F-59000 Lille, France.ORCID 0009-0000-4407-2178
Emmanuel ForestierService de Maladies Infectieuses, Centre Hospitalier Métropole Savoie, F-73000 Chambéry, France.
Gaëtan GavazziClinique Universitaire de Médecine Gériatrique, Centre Hospitalier Universitaire de Grenoble-Alpes, GREPI EA7408 Université Grenoble-Alpes, F-38000 Grenoble, France.
Claire Roubaud-BaudronCHU Bordeaux, Pôle de Gérontologie Clinique, University of Bordeaux, INSERM 1312 BRIC, F-33000 Bordeaux, France.ORCID 0000-0003-0870-0979
Vincent HiernardCHU Lille, University of Lille, F-59000 Lille, France.
Rozenn Hequette-RuzService de Maladies Infectieuses, CH Roubaix, F-59056 Roubaix, France.
Serge AlfandariService Universitaire de Maladies Infectieuses et Tropicales, Hôpital Gustave Dron, F-59200 Tourcoing, France.ORCID 0000-0002-9672-725X
Hugues AumaîtreService de Maladies Infectieuses et Tropicales, Centre Hospitalier de Perpignan, F-66000 Perpignan, France.ORCID 0000-0002-0023-7652
Elisabeth Botelho-NeversInfectious Diseases Department, University Hospital of Saint-Etienne, GIMAP (EA 3064), F-42055 Cedex 02 Saint-Etienne, France.
Pauline Caraux-PazService de Maladies Infectieuses et Tropicales, Hôpital Intercommunal de Villeneuve-Saint-Georges, F-94190 Villeneuve-Saint-Georges, France.ORCID 0000-0003-4832-0161
Alexandre CharmillonCHRU-Nancy, Infectious Diseases Department, F-54000 Nancy, France.
Sylvain DiamantisService de Maladies Infectieuses et Tropicales, Hôpital de Melun, F-77000 Melun, France.
Thibaut FraisseCourt Séjour Gériatrique Aigu, Centre Hospitalier Alès-Cévennes, F-30100 Alès, France.ORCID 0000-0002-2388-1838
Pierre GazeauService des Maladies Infectieuses et Tropicales, CHRU de Brest, F-29609 Brest Cedex, France.ORCID 0000-0003-2934-7617
Maxime HentzienDepartment of Internal Medicine, Infectious Diseases and Clinical Immunology, University Hospital of Reims, F-51100 Reims, France.ORCID 0000-0003-2729-9420
Jean-Philippe LanoixAGIR UR 4294, University Picardie Jules Verne, F-80000 Amiens, France.
Marc PaccalinPôle de Gériatrie, CHU Poitiers, Université Poitiers, F-86000 Poitiers, France.
Alain PutotMédecine Interne et Maladies Infectieuses, Hôpitaux du Pays du Mont Blanc, F-74700 Sallanches, France.
Yvon RuchDepartment of Infectious Diseases, Strasbourg University Hospital, F-67000 Strasbourg, France.ORCID 0000-0002-4713-9478
Eric SennevilleService Universitaire de Maladies Infectieuses et Tropicales, Hôpital Gustave Dron, F-59200 Tourcoing, France.
Jean-Baptiste BeuscartCHU Lille, University of Lille, F-59000 Lille, France.
GInGer (SPILF–SFGG Study Group)
Centre Hospitalier de Tourcoing · FRUniversité de Lille · FRCentre Hospitalier de Perpignan · FRCentre Hospitalier de Roubaix · FRCentre Hospitalier Intercommunal de Villeneuve-Saint-Georges · FRCentre Hospitalier Métropole Savoie · FRCentre Hospitalier Régional et Universitaire de Nancy · FRCentre Hospitalier Régional Universitaire de Brest · FRCentre Hospitalier Universitaire Amiens-Picardie · FRCentre Hospitalier Universitaire de Grenoble · FRCentre Hospitalier Universitaire de Reims · FRInserm · FRUniversité Catholique de Lille · FRUniversité Claude Bernard Lyon 1 · FRUniversité de Bordeaux · FRUniversité de Bourgogne · FRUniversité de Strasbourg · FRUniversité Paris-Est Créteil · FR

Funding

Stop Sida Association NA
6 · The paper itself

Abstract

backgroundIn geriatrics, explicit criteria for potentially inappropriate prescriptions (PIPs) are useful for optimizing drug use.

objectiveTo produce an expert consensus on explicit definitions of antibiotic-PIPs for hospitalized older patients.

methodsWe conducted a Delphi survey involving French experts on antibiotic stewardship in hospital settings. During the survey's rounds, the experts gave their opinion on each explicit definition, and could suggest new definitions. Definitions with a 1-to-9 Likert score of between 7 and 9 from at least 75% of the participants were adopted. The results were discussed during consensus meetings after each round.

resultsOf the 155 invited experts, 128 (82.6%) participated in the whole survey: 59 (46%) infectious diseases specialists, 45 (35%) geriatricians, and 24 (19%) other specialists. In Round 1, 65 explicit definitions were adopted and 21 new definitions were suggested. In Round 2, 35 other explicit definitions were adopted. The results were validated during consensus meetings (with 44 participants after Round 1, and 54 after Round 2).

conclusionsThe present study is the first to have provided a list of explicit definitions of potentially inappropriate antibiotic prescriptions for hospitalized older patients. It might help to disseminate key messages to prescribers and reduce inappropriate prescriptions of antibiotics.

Indexed as

antibiotic stewardshipantimicrobial resistanceelderlyhospital settinginappropriate prescription

Identifiers

PMID38534718
PMCPMC10967330
OpenAlexW4392983451

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.