Evidence map›Paper›PMID 38534703›Full record

ReviewAntibiotics (Basel, Switzerland)2024

Rethinking Hidradenitis Suppurativa Management: Insights into Bacterial Interactions and Treatment Evolution.

Faith D Huynh, Giovanni Damiani, Christopher G Bunick

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Low Dose Intravenous Ertapenem for Hidradenitis Suppurativa.International journal of dermatology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Hidradenitis Suppurativa Tunnels: Unveiling a Unique Disease Entity.JID innovations : skin science from molecules to population health · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Faith D HuynhYale School of Medicine, New Haven, CT 06510, USA.ORCID 0009-0001-6697-9608
Giovanni DamianiDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-2390-6505
Christopher G BunickDepartment of Dermatology and Program in Translational Biomedicine, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-4011-8308
Yale University · USUniversity of Milan · IT

Funding

Molecular function of an intermediate filament assembly mechanism in epidermal protein complexes and cell migrationR01AR079428 · NIAMS · YALE UNIVERSITY · PI BUNICK, CHRISTOPHER GERARD · 2021 to 2025
$1.8M
NIAMS NIH HHS R01 AR079428
6 · The paper itself

Abstract

Hidradenitis suppurativa (HS), or acne inversa, is a chronic inflammatory dermatological condition characterized by painful and recurrent nodules and purulent abscesses. HS can have a devastating impact on the quality of life of patients. This condition is commonly localized to the axilla, groin, perineal, and inframammary regions, and can develop fistulas and sinus tracts over time. Its pathogenesis remains elusive and is best characterized at the moment as multi-factorial. Additionally, questions remain about the role of cutaneous dysbiosis as a primary HS trigger or as a secondary perturbation due to HS inflammation. This article features works in relation to HS and its interplay with bacterial microflora. We address current treatment approaches and their impact on HS-related bacteria, as well as areas of therapeutic innovation. In the future, disease-modifying or remittive therapy will likely combine an advanced/targeted anti-inflammatory approach with one that effectively modulates cutaneous and deep tissue dysbiosis.

Indexed as

acne inversaanaerobesantibioticsbacteriabiofilm formationbiologicsdermatologyinflammatory skin diseaseJAK inhibitorsresistance

Identifiers

PMID38534703
PMCPMC10967558
OpenAlexW4392913183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.