Evidence map›Paper›PMID 38534693›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Intrapulmonary and Systemic Pharmacokinetics of Colistin Following Nebulization of Low-Dose Colistimethate Sodium in Patients with Ventilator-Associated Pneumonia Caused by Carbapenem-Resistant

Dong-Hwan Lee, Shin-Young Kim, Yong-Kyun Kim, So-Young Jung, Ji-Hoon Jang, Hang-Jea Jang, Jae-Ha Lee

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dong-Hwan LeeDepartment of Clinical Pharmacology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14066, Republic of Korea.ORCID 0000-0002-8681-099X
Shin-Young KimDepartment of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon 16247, Republic of Korea.ORCID 0000-0001-5460-2005
Yong-Kyun KimDivision of Infectious Diseases, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14066, Republic of Korea.
So-Young JungDepartment of Dermatology, Inje University Haeundae Paik Hospital, Busan 48108, Republic of Korea.
Ji-Hoon JangDivision of Pulmonology and Critical Care Medicine, Inje University Haeundae Paik Hospital, Busan 48108, Republic of Korea.
Hang-Jea JangDivision of Pulmonology and Critical Care Medicine, Inje University Haeundae Paik Hospital, Busan 48108, Republic of Korea.
Jae-Ha LeeDivision of Pulmonology and Critical Care Medicine, Inje University Haeundae Paik Hospital, Busan 48108, Republic of Korea.
Inje University Haeundae Paik Hospital · KRHallym University Sacred Heart Hospital · KRThe Catholic University of Korea St. Vincent's Hospital · KR

Funding

National Research Foundation of Korea 2020R1F1A1077190
6 · The paper itself

Abstract

Colistimethate sodium (CMS) nebulization is associated with reduced systemic toxicity compared to intravenous injection, with potentially enhanced clinical efficacy. This study aimed to assess the pharmacokinetic (PK) properties of colistin during low-dose CMS nebulization in patients with ventilator-associated pneumonia (VAP) caused by carbapenem-resistant

Indexed as

carbapenem-resistant Acinetobacter baumanniicolistimethate sodiumcolistinepithelial lining fluidinhalationnebulizationplasmapopulation pharmacokineticsventilator-associated pneumonia

Identifiers

PMID38534693
PMCPMC10967270
OpenAlexW4392846076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.