Evidence map›Paper›PMID 38534634›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Fungal Endophthalmitis: Clinical Characteristics, Pathogens, and Factors Affecting Visual Outcome.

Xiaoxia Li, Zhi Chen, Xiuwen Zhang, Zimei Zhou, Maureen Boost, Taomin Huang, Xingtao Zhou

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Safety and efficacy of echinocandin antifungal agents inAntimicrobial agents and chemotherapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Xiaoxia LiDepartment of Pharmacy, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.ORCID 0009-0000-6385-7421
Zhi ChenEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
Xiuwen ZhangDepartment of Pharmacy, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.ORCID 0000-0003-3138-7466
Zimei ZhouDepartment of Ophthalmology, BronxCare Health System, Bronx, NY 10456, USA.
Maureen BoostSchool of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR 999077, China.
Taomin HuangDepartment of Pharmacy, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.ORCID 0000-0001-5580-8371
Xingtao ZhouEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
Eye & ENT Hospital of Fudan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNHong Kong Polytechnic University · HKMontefiore Health System · US

Funding

Clinical Research Plan of SHDC SHDC2020CR1043BProject of Shanghai Xuhui District Science and Technology 2020-015Project of Shanghai Xuhui District Science and Technology XHLHGG202104the Shanghai Municipal Health Commission 202140069
6 · The paper itself

Abstract

aimsThe aims of this study are to investigate the etiology, microbiological spectrum, and risk factors associated with visual outcomes of fungal endophthalmitis (FE) in a tertiary eye specialty hospital in Shanghai, China.

methodsThis was a retrospective, single-center case series. The clinical characteristics, etiology, microbiological spectrum, and management, as well as the visual outcomes, were analyzed. Logistic regression was used to analyze the factors related to visual outcomes.

resultsThis study involved 102 eyes of 92 patients with FE, including 63 males (66.3%). The mean age was 44.4 ± 19.8 years. The most common etiology of FE was trauma (56.5%). The predominant fungal species isolated were

conclusionsEarly diagnosis of FE and a timely vitrectomy, combined with an intravitreal injection of an antifungal drug, can mitigate the devastating results of intraocular fungal infection. Not being infected by

Indexed as

Aspergillus speciesCandida speciescorneal infiltrateFungal endophthalmitispars plana vitrectomyvisual outcomevoriconazole

Identifiers

PMID38534634
PMCPMC10967284
OpenAlexW4391953724

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.