Evidence map›Paper›PMID 38534548›Full record

ArticleBioengineering (Basel, Switzerland)2024

Correlation between Malocclusion and Mandibular Fractures: An Experimental Study Comparing Dynamic Finite Element Models and Clinical Case Studies.

Giorgio Novelli, Andrea Filippi, Andrea Cartocci, Sergio Mirabella, Marco Talarico, Elena De Ponti, Maria Costanza Meazzini, Davide Sozzi, Gabriele Canzi, Marco Anghileri

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Giorgio NovelliO.U. Maxillofacial Surgery, Department of Medicine and Surgery, School of Medicine, IRCCS San Gerardo dei Tintori Foundation, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, Italy.ORCID 0000-0003-2357-6726
Andrea FilippiO.U. Maxillofacial Surgery, Department of Medicine and Surgery, School of Medicine, IRCCS San Gerardo dei Tintori Foundation, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, Italy.ORCID 0000-0003-0230-5476
Andrea CartocciO.U. Maxillofacial Surgery, Department of Medicine and Surgery, School of Medicine, IRCCS San Gerardo dei Tintori Foundation, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, Italy.
Sergio MirabellaO.U. Maxillofacial Surgery, Department of Medicine and Surgery, School of Medicine, IRCCS San Gerardo dei Tintori Foundation, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, Italy.
Marco TalaricoDepartment of Aerospace Science and Technology, Politecnico di Milano, Via La Masa 34, 20156 Milan, Italy.
Elena De PontiDepartment of Medical Physics, IRCCS San Gerardo dei Tintori Foundation, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, Italy.
Maria Costanza MeazziniO.U. Maxillofacial Surgery, Department of Medicine and Surgery, School of Medicine, IRCCS San Gerardo dei Tintori Foundation, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, Italy.
Davide SozziO.U. Maxillofacial Surgery, Department of Medicine and Surgery, School of Medicine, IRCCS San Gerardo dei Tintori Foundation, University of Milano-Bicocca, Via Pergolesi 33, 20900 Monza, Italy.ORCID 0000-0002-6281-5307
Gabriele CanziMaxillofacial Surgery Unit, Emergency Department, ASST-GOM Niguarda, Niguarda Hospital, Piazza Ospedale Maggiore 3, 20162 Milan, Italy.ORCID 0000-0002-2513-369X
Marco AnghileriDepartment of Aerospace Science and Technology, Politecnico di Milano, Via La Masa 34, 20156 Milan, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITPolitecnico di Milano · ITUniversity of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mandibular fractures are very common in maxillofacial trauma surgery. While previous studies have focused on possible risk factors related to post-operative complications, none have tried to identify pre-existing conditions that may increase the risk of mandibular fractures. We hypothesized, through clinical observation, that anatomical conditions involving poor dental contacts, such as malocclusions, may increase the risk of mandibular fractures. This work was subdivided into two parts. In the first part, Digital Imaging and Communications in Medicine (DICOM) data of four healthy patients characterized by different dentoskeletal occlusions (class I, class II, class III, and anterior open bite) have been used to develop four finite element models (FEMs) that accurately reproduce human bone structure. A vertical and lateral impact have been simulated at increasing speed on each model, analyzing the force distribution within the mandibular bone. Both vertical and lateral impact showed higher level of stress at the impact point and in the condylar area in models characterized by malocclusion. Specifically, the class III and the open bite models, at the same speed of impact, had higher values for a longer period, reaching critical stress levels that are correlated with mandibular fracture, while normal occlusion seems to be a protective condition. In the second part of this study, the engineering results were validated through the comparison with a sample of patients previously treated for mandibular fracture. Data from 223 mandibular fractures, due to low-energy injuries, were retrospectively collected to evaluate a possible correlation between pre-existing malocclusion and fracture patterns, considering grade of displacement, numbers of foci, and associated CFI score. Patients were classified, according to their occlusion, into Class I, Class II, Class III, and anterior open bite or poor occlusal contact (POC). Class I patients showed lower frequencies of fracture than class II, III, and open bite or POC patients. Class I was associated with displaced fractures in 16.1% of cases, class II in 47.1%, class III in 48.8% and open bite/POC in 65.2% of cases (

Indexed as

dental occlusionfinite element analysisfinite element modelmalocclusion class IImalocclusion class IIImandibular condylemandibular fractureopen bite

Identifiers

PMID38534548
PMCPMC10968614
OpenAlexW4392751510

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.