Evidence map›Paper›PMID 38534534›Full record

ArticleBioengineering (Basel, Switzerland)2024

Monte Carlo-Based Optical Simulation of Optical Distribution in Deep Brain Tissues Using Sixteen Optical Sources.

Xi Yang, Chengpeng Chai, Hongzhi Zuo, Yun-Hsuan Chen, Junhui Shi, Cheng Ma, Mohamad Sawan

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xi YangCollege of Biomedical Engineering & Instrument Science, Zhejiang University, 38 Zheda Road, Hangzhou 310013, China.ORCID 0000-0002-7054-616X
Chengpeng ChaiCenBRAIN Neurotech Center of Excellence, School of Engineering, Westlake University, 600 Dunyu Road, Xihu District, Hangzhou 310030, China.ORCID 0009-0008-6964-3289
Hongzhi ZuoBeijing National Research Center for Information Science and Technology, Department of Electronic Engineering, Tsinghua University, 30, Shuangqing Road, Haidian District, Beijing 100084, China.
Yun-Hsuan ChenCenBRAIN Neurotech Center of Excellence, School of Engineering, Westlake University, 600 Dunyu Road, Xihu District, Hangzhou 310030, China.ORCID 0000-0002-3431-1806
Junhui ShiZhejiang Lab, 1 Kechuang Avenue, Yuhang District, Hangzhou 311100, China.
Cheng MaBeijing National Research Center for Information Science and Technology, Department of Electronic Engineering, Tsinghua University, 30, Shuangqing Road, Haidian District, Beijing 100084, China.
Mohamad SawanCenBRAIN Neurotech Center of Excellence, School of Engineering, Westlake University, 600 Dunyu Road, Xihu District, Hangzhou 310030, China.ORCID 0000-0002-4137-7272

Funding

Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang 2020R01005Westlake University 041030080118
6 · The paper itself

Abstract

Optical-based imaging has improved from early single-location research to further sophisticated imaging in 2D topography and 3D tomography. These techniques have the benefit of high specificity and non-radiative safety for brain detection and therapy. However, their performance is limited by complex tissue structures. To overcome the difficulty in successful brain imaging applications, we conducted a simulation using 16 optical source types within a brain model that is based on the Monte Carlo method. In addition, we propose an evaluation method of the optical propagating depth and resolution, specifically one based on the optical distribution for brain applications. Based on the results, the best optical source types were determined in each layer. The maximum propagating depth and corresponding source were extracted. The optical source propagating field width was acquired in different depths. The maximum and minimum widths, as well as the corresponding source, were determined. This paper provides a reference for evaluating the optical propagating depth and resolution from an optical simulation aspect, and it has the potential to optimize the performance of optical-based techniques.

Indexed as

brain imagingfunctional near-infrared spectroscopy (fNIRS)Monte Carlo simulationoptical imagingoptical simulationoptogeneticsphotoacoustic imaging

Identifiers

PMID38534534
PMCPMC10968032

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.