Evidence map›Paper›PMID 38534431›Full record

ReviewBiology2024

Influence of Brainstem's Area A5 on Sympathetic Outflow and Cardiorespiratory Dynamics.

Isabel Rocha, Marta González-García, Laura Carrillo-Franco, Marc Stefan Dawid-Milner, Manuel Victor López-González

Open access · goldAbstract readReview
In one paragraph

Review in Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Isabel RochaLisbon School of Medicine and CCUL@Rise, Universidade de Lisboa, 1649-028 Lisbon, Portugal.
Marta González-GarcíaDepartment of Human Physiology, Faculty of Medicine, University of Malaga, 29590 Malaga, Spain.ORCID 0000-0003-4085-7757
Laura Carrillo-FrancoDepartment of Human Physiology, Faculty of Medicine, University of Malaga, 29590 Malaga, Spain.
Marc Stefan Dawid-MilnerDepartment of Human Physiology, Faculty of Medicine, University of Malaga, 29590 Malaga, Spain.
Manuel Victor López-GonzálezDepartment of Human Physiology, Faculty of Medicine, University of Malaga, 29590 Malaga, Spain.ORCID 0000-0001-9023-3710
Instituto de Investigación Biomédica de Málaga · ESUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Area A5 is a noradrenergic cell group in the brain stem characterised by its important role in triggering sympathetic activity, exerting a profound influence on the sympathetic outflow, which is instrumental in the modulation of cardiovascular functions, stress responses and various other physiological processes that are crucial for adaptation and survival mechanisms. Understanding the role of area A5, therefore, not only provides insights into the basic functioning of the sympathetic nervous system but also sheds light on the neuronal basis of a number of autonomic responses. In this review, we look deeper into the specifics of area A5, exploring its anatomical connections, its neurochemical properties and the mechanisms by which it influences sympathetic nervous system activity and cardiorespiratory regulation and, thus, contributes to the overall dynamics of the autonomic function in regulating body homeostasis.

Indexed as

area A5autonomic responsebrainstem neurochemistrycardiovascular regulationsympathetic nervous system

Identifiers

PMID38534431
PMCPMC10967927
OpenAlexW4392375483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.