Evidence map›Paper›PMID 38534423›Full record

ReviewBiology2024

Research Progress of Nanomaterials Acting on NK Cells in Tumor Immunotherapy and Imaging.

Yachan Feng, Haojie Zhang, Jiangtao Shao, Chao Du, Xiaolei Zhou, Xueling Guo, Yingze Wang

Open access · goldAbstract readReview
In one paragraph

Review in Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yachan FengCollege of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Haojie ZhangCollege of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Jiangtao ShaoCollege of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Chao DuCollege of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Xiaolei ZhouCollege of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Xueling GuoCollege of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Yingze WangCollege of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.ORCID 0000-0003-2775-5166
Hebei University of Science and Technology · CN

Funding

Doctoral research fund project of Hebei university of science and technology no.QD2023004Graduate Student Innovation Ability Training project of Hebei University of Science and Technology no.XJCXZZSS202307National Natural Science Foundation of China no.81760750Natural Science Foundation of Hebei Province no.C2020208023Natural Science Foundation of Hebei Province no.H2020208018
6 · The paper itself

Abstract

The prognosis for cancer patients has declined dramatically in recent years due to the challenges in treating malignant tumors. Tumor immunotherapy, which includes immune target inhibition and chimeric antigen receptor cell treatment, is currently evolving quickly. Among them, natural killer (NK) cells are gradually becoming another preferred cell immunotherapy after T cell immunotherapy due to their unique killing effects in innate and adaptive immunity. NK cell therapy has shown encouraging outcomes in clinical studies; however, there are still some problems, including limited efficacy in solid tumors, inadequate NK cell penetration, and expensive treatment expenses. Noteworthy benefits of nanomaterials include their chemical specificity, biocompatibility, and ease of manufacturing; these make them promising instruments for enhancing NK cell anti-tumor immune responses. Nanomaterials can promote NK cell homing and infiltration, participate in NK cell modification and non-invasive cell tracking and imaging modes, and greatly increase the effectiveness of NK cell immunotherapy. The introduction of NK cell-based immunotherapy research and a more detailed discussion of nanomaterial research in NK cell-based immunotherapy and molecular imaging will be the main topics of this review.

Indexed as

drug carriernanomaterialsNK cell immunotherapytarget blocktumor immunotherapy

Identifiers

PMID38534423
PMCPMC10967831
OpenAlexW4392189070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.