Evidence map›Paper›PMID 38534390›Full record

ArticleCells2024

Comparison of Minced Cartilage Implantation with Autologous Chondrocyte Transplantation in an In Vitro Inflammation Model.

Robert Ossendorff, Lisa Grede, Sebastian Scheidt, Andreas C Strauss, Christof Burger, Dieter C Wirtz, Gian M Salzmann, Frank A Schildberg

Open access · goldAbstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Robert OssendorffDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-6636-8065
Lisa GredeDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Sebastian ScheidtDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-7852-2277
Andreas C StraussDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0001-7777-3253
Christof BurgerDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Dieter C WirtzDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Gian M SalzmannGelenkzentrum Rhein-Main, 65239 Hochheim, Germany.
Frank A SchildbergDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0003-0797-1945
University Hospital Bonn · DESchulthess-Klinik · CH

Funding

BONFOR-Forschungskommission der Medizinischen Fakultät Bonn N/ADeutsche Arthrosehilfe e.V. N/ADeutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy EXC2151 - 390873048
6 · The paper itself

Abstract

The current gold standard to treat large cartilage defects is autologous chondrocyte transplantation (ACT). As a new surgical method of cartilage regeneration, minced cartilage implantation (MCI) is increasingly coming into focus. The aim of this study is to investigate the influence of chondrogenesis between isolated and cultured chondrocytes compared to cartilage chips in a standardized inflammation model with the proinflammatory cytokine TNFα. Articular chondrocytes from bovine cartilage were cultured according to the ACT method to passage 3 and transferred to spheroid culture. At the same time, cartilage was fragmented (<1 mm

Indexed as

ChondrocytesTumor Necrosis Factor-alphaAnimalsCartilageCattleCytokinesInflammationCytokinesTumor Necrosis Factor-alphaautologous chondrocyte transplantationinflammation modelminced cartilage implantationmusculoskeletal immunologytumor necrosis factor α

Identifiers

PMID38534390
PMCPMC10969176
OpenAlexW4393005943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.