Evidence map›Paper›PMID 38534345›Full record

ReviewCells2024

Molecular Mechanism of Autophagosome-Lysosome Fusion in Mammalian Cells.

Po-Yuan Ke

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
19.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Regulation of Innate Immune Signaling by Autophagy.International journal of molecular sciences · 2026
    Review
  9. Review
  10. Review
  11. Autophagy: A Double-Edged Sword in the Aging ofInternational journal of molecular sciences · 2026
    Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. The role of autophagy in protozoan infections.Frontiers in cellular and infection microbiology · 2026
    Review
  18. Frontiers in cell and developmental biology · 2026
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Po-Yuan KeDepartment of Biochemistry & Molecular Biology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-0471-0806
Chang Gung University · TW

Funding

Chang Gung Memorial Hospital CMRPD1M0671, CMRPD1N0221, CMRPD1N0431, and BMRPD01National Health Research Institute NHRI-EX103-10322SC, NHRI-EX104-10322SC, NHRI-EX105-10322SC and NHRI-EX106-10322SCNational Science and Technology Council MOST 109-2320-B-182-010-MY3
6 · The paper itself

Abstract

In eukaryotes, targeting intracellular components for lysosomal degradation by autophagy represents a catabolic process that evolutionarily regulates cellular homeostasis. The successful completion of autophagy initiates the engulfment of cytoplasmic materials within double-membrane autophagosomes and subsequent delivery to autolysosomes for degradation by acidic proteases. The formation of autolysosomes relies on the precise fusion of autophagosomes with lysosomes. In recent decades, numerous studies have provided insights into the molecular regulation of autophagosome-lysosome fusion. In this review, an overview of the molecules that function in the fusion of autophagosomes with lysosomes is provided. Moreover, the molecular mechanism underlying how these functional molecules regulate autophagosome-lysosome fusion is summarized.

Indexed as

AutophagosomesAutophagyAnimalsHomeostasisLysosomesMacroautophagyMammalsautolysosomeautophagosomeautophagosome–lysosome fusionautophagylysosome

Identifiers

PMID38534345
PMCPMC10968809
OpenAlexW4392763450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.