Evidence map›Paper›PMID 38534330›Full record

ArticleCells2024

Cannabidiol Disrupts Mitochondrial Respiration and Metabolism and Dysregulates Trophoblast Cell Differentiation.

Tina Podinic, Louise Limoges, Cristina Monaco, Andie MacAndrew, Mahek Minhas, Joshua Nederveen, Sandeep Raha

Open access · goldAbstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. The effects of Cannabidiol on podocytes in vitro.Biochemical and biophysical research communications · 2025
    Article
  8. The impact of cannabinoids on reproductive function.Reproduction (Cambridge, England) · 2025
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tina PodinicGraduate Program in Medical Sciences, Department of Pediatrics, McMaster University, 1280 Main St. W., Hamilton, ON L8S 4K1, Canada.
Louise LimogesGraduate Program in Medical Sciences, Department of Pediatrics, McMaster University, 1280 Main St. W., Hamilton, ON L8S 4K1, Canada.
Cristina MonacoGraduate Program in Medical Sciences, Department of Pediatrics, McMaster University, 1280 Main St. W., Hamilton, ON L8S 4K1, Canada.
Andie MacAndrewGraduate Program in Medical Sciences, Department of Pediatrics, McMaster University, 1280 Main St. W., Hamilton, ON L8S 4K1, Canada.
Mahek MinhasDepartment of Pediatrics, McMaster University, 1280 Main St. W., Hamilton, ON L8S 4K1, Canada.
Joshua NederveenDepartment of Pediatrics, McMaster University, 1280 Main St. W., Hamilton, ON L8S 4K1, Canada.
Sandeep RahaGraduate Program in Medical Sciences, Department of Pediatrics, McMaster University, 1280 Main St. W., Hamilton, ON L8S 4K1, Canada.
McMaster University · CA

Funding

Michael DeGroote Medicinal Cannabis Research Centre 2022Natural Sciences and Engineering Research Council RGPIN-2020-06739
6 · The paper itself

Abstract

Trophoblast differentiation is a crucial process in the formation of the placenta where cytotrophoblasts (CTs) differentiate and fuse to form the syncytiotrophoblast (ST). The bioactive components of cannabis, such as Δ

Indexed as

CannabidiolCell DifferentiationFemaleHumansMitochondriaPregnancyRNA, MessengerTrophoblastsCannabidiolRNA, Messengercannabiscytotrophoblastdifferentiationendocannabinoid systemmitochondriaoxidative stressplacentationpregnancysyncytiotrophoblasttrophoblast

Identifiers

PMID38534330
PMCPMC10968792
OpenAlexW4392661211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.