Evidence map›Paper›PMID 38534309›Full record

SynthesisCells2024

Role of Surgery in Metastatic Melanoma and Review of Melanoma Molecular Characteristics.

Kulkaew Sukniam, Harsheen K Manaise, Kyle Popp, Reed Popp, Emmanuel Gabriel

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Kulkaew SukniamDepartment of General Surgery, Duke University Medical Center, Durham, NC 27707, USA.
Harsheen K ManaiseDepartment of Medicine, Government Medical College and Hospital, Chandigarh 160047, India.
Kyle PoppDepartment of Medicine, Florida State University, Tallahassee, FL 32306, USA.
Reed PoppCollege of Medicine, University of Florida, Gainesville, FL 32611, USA.
Emmanuel GabrielDepartment of General Surgery, Division of Surgical Oncology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.ORCID 0000-0001-8570-4784
Duke Medical Center · USFlorida State University · USGovernment Medical College and Hospital · INMayo Clinic in Florida · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to review the molecular characteristics of metastatic melanoma and the role of surgery in metastasectomy for metastatic melanoma. We performed a systematic literature search on PubMed to identify relevant studies focusing on several mutations, including NRAS, BRAF, NF1, MITF, PTEN, TP53, CDKN2A, TERT, TMB, EGFR, and c-KIT. This was performed in the context of metastatic melanoma and the role of metastasectomy in the metastatic melanoma population. A comprehensive review of these molecular characteristics is presented with a focus on their prognosis and role in surgical metastasectomy.

Indexed as

MelanomaSkin NeoplasmsGTP PhosphohydrolasesHumansMembrane ProteinsProto-Oncogene Proteins B-rafGTP PhosphohydrolasesMembrane ProteinsProto-Oncogene Proteins B-rafmelanomametastatic melanomamutationsurgery

Identifiers

PMID38534309
PMCPMC10969165
OpenAlexW4392562165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.