Evidence map›Paper›PMID 38534252›Full record

ReviewBiosensors2024

Detection of Parasites in the Field: The Ever-Innovating CRISPR/Cas12a.

Xin Li, Zhisheng Dang, Wenqiang Tang, Haoji Zhang, Jianwei Shao, Rui Jiang, Xu Zhang, Fuqiang Huang

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Theileria annulata diagnostics: past, present and future.Tropical animal health and production · 2026
    Review
  3. Review
  4. Article
  5. Next-generation molecular tools in veterinary parasitology: advances, challenges, and perspectives in the diagnosis of emerging parasites.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2026
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Rapid and sensitive detection of bovineFrontiers in microbiology · 2025
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Xin LiSchool of Life Science and Engineering, Foshan University, Foshan 528225, China.ORCID 0000-0002-6423-3060
Zhisheng DangNational Institute of Parasitic Diseases, Chinese Center for Diseases Control and Prevention (Chinese Center for Tropical Diseases Research), Key Laboratory of Parasite and Vector Biology, National Health Commission of the People's Republic of China (NHC), World Health Organization (WHO) Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China.
Wenqiang TangState Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement, Lhasa 850002, China.
Haoji ZhangSchool of Life Science and Engineering, Foshan University, Foshan 528225, China.
Jianwei ShaoSchool of Life Science and Engineering, Foshan University, Foshan 528225, China.ORCID 0000-0001-9548-3831
Rui JiangCollege of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Xu ZhangSchool of Life Science and Engineering, Foshan University, Foshan 528225, China.
Fuqiang HuangSchool of Life Science and Engineering, Foshan University, Foshan 528225, China.ORCID 0000-0002-3613-2350
Foshan University · CNHuazhong Agricultural University · CNNational Institute for Parasitic Diseases · CNTibet Academy of Agricultural and Animal Husbandry Sciences · CN

Funding

Open Project Program of State Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement XZNKY-CZ-2022-016-08
6 · The paper itself

Abstract

The rapid and accurate identification of parasites is crucial for prompt therapeutic intervention in parasitosis and effective epidemiological surveillance. For accurate and effective clinical diagnosis, it is imperative to develop a nucleic-acid-based diagnostic tool that combines the sensitivity and specificity of nucleic acid amplification tests (NAATs) with the speed, cost-effectiveness, and convenience of isothermal amplification methods. A new nucleic acid detection method, utilizing the clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) nuclease, holds promise in point-of-care testing (POCT). CRISPR/Cas12a is presently employed for the detection of

Indexed as

Body FluidsParasitesAnimalsBiological AssayCRISPR-Cas SystemsNucleic Acid Amplification TechniquesRNA, Guide, CRISPR-Cas SystemsRNA, Guide, CRISPR-Cas SystemsCas12aCRISPRdetectionlight-activated crRNAPOCTsuboptimal crRNAtandem repeats

Identifiers

PMID38534252
PMCPMC10968006
OpenAlexW4392850929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.