Evidence map›Paper›PMID 38534131›Full record

Trial reportEnvironmental health perspectives2024

Effect of an Arsenic Mitigation Program on Arsenic Exposure in American Indian Communities: A Cluster Randomized Controlled Trial of the Community-Led Strong Heart Water Study Program.

Christine Marie George, Tracy Zacher, Kelly Endres, Francine Richards, Lisa Bear Robe, David Harvey, Lyle G Best, Reno Red Cloud, Annabelle Black Bear, Leslie Skinner and 12 more

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Environmental health perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 1 country.

Christine Marie GeorgeDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Tracy ZacherMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Kelly EndresDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Francine RichardsMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Lisa Bear RobeMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
David HarveyIndian Health Service, Rockville, Maryland, USA.
Lyle G BestMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Reno Red CloudEnvironmental Resource Department, Oglala Sioux Tribe, Pine Ridge, South Dakota, USA.
Annabelle Black BearMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Leslie SkinnerMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Christa CunyMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Ana RuleDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Kellogg J SchwabDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Joel GittelsohnDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Ronald Alexander GlabonjatDepartment of Environmental Health Science, Mailman School of Public Health, Columbia University, New York, New York, USA.
Kathrin SchillingDepartment of Environmental Health Science, Mailman School of Public Health, Columbia University, New York, New York, USA.
Marcia O'LearyMissouri Breaks Industries Research Inc., Eagle Butte, South Dakota, USA.
Elizabeth D ThomasDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Jason UmansBiomarker, Biochemistry, and Biorepository Core, Medstar Health, Washington, District of Columbia, USA.
Jianhui ZhuBiomarker, Biochemistry, and Biorepository Core, Medstar Health, Washington, District of Columbia, USA.
Lawrence H MoultonDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Ana Navas-AcienDepartment of Environmental Health Science, Mailman School of Public Health, Columbia University, New York, New York, USA.
Missouri Breaks Industries Research (United States) · USJohns Hopkins University · USColumbia University · USGeorgetown University · USIndian Health Service · USMedStar Health · USOglala Sioux Tribal Council · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Research Experience and Training Coordination CoreP42ES033719 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Ana Navas-Acien · 2022 to 2026
$11.9M
Participatory Interventions to Reduce Arsenic in American Indian CommunitiesR01ES025135 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI GEORGE, CHRISTINE MARIE, NAVAS-ACIEN, ANA · 2015 to 2019
$2.8M
NIEHS NIH HHS P30 ES009089NIEHS NIH HHS P42 ES033719NIEHS NIH HHS R01 ES025135
6 · The paper itself

Abstract

backgroundChronic arsenic exposure has been associated with an increased risk of cardiovascular disease; diabetes; cancers of the lung, pancreas and prostate; and all-cause mortality in American Indian communities in the Strong Heart Study.

objectiveThe Strong Heart Water Study (SHWS) designed and evaluated a multilevel, community-led arsenic mitigation program to reduce arsenic exposure among private well users in partnership with Northern Great Plains American Indian Nations.

methodsA cluster randomized controlled trial (cRCT) was conducted to evaluate the effectiveness of the SHWS arsenic mitigation program over a 2-y period on

resultsA 47% reduction in urinary arsenic [ DISCUSSION: Delivery of the interventions for the community-led SHWS arsenic mitigation program, including the installation of a point-of-use arsenic filter and a mHealth program on the use of arsenic-safe water (calls only, no home visits), resulted in a significant reduction in urinary arsenic and increases in reported use of arsenic-safe water for drinking and cooking during the 2-y study period. These results demonstrate that the installation of an arsenic filter and phone calls from a mHealth program presents a promising approach to reduce water arsenic exposure among private well users. https://doi.org/10.1289/EHP12548.

Indexed as

ArsenicDrinking WaterAmerican Indian or Alaska NativeCreatinineHumansTelemedicineArsenicCreatinineDrinking Water

Identifiers

PMID38534131
PMCPMC10967367
OpenAlexW4393223736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.