Evidence map›Paper›PMID 38534093›Full record

ArticleJournal of cellular and molecular medicine2024

Hepatoprotective activity of Lactéol® forte and quercetin dihydrate against thioacetamide-induced hepatic cirrhosis in male albino rats.

Hebatallah M Saad, Samah S Oda, Athanasios Alexiou, Marios Papadakis, Mohamed H Mahmoud, Gaber El-Saber Batiha, Eman Khalifa

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Hebatallah M SaadDepartment of Pathology, Faculty of Veterinary Medicine, Matrouh University, Matrouh, Egypt.ORCID 0000-0001-9555-7300
Samah S OdaDepartment of Pathology, Faculty of Veterinary Medicine, Alexandria University, Abees, Alexandria Province, Egypt.
Athanasios AlexiouUniversity Centre for Research & Development, Chandigarh University, Mohali, Punjab, India.ORCID 0000-0002-2206-7236
Marios PapadakisDepartment of Surgery II, University Hospital Witten-Herdecke, Heusnerstrasse 40, University of Witten-Herdecke, Wuppertal, Germany.
Mohamed H MahmoudDepartment of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Gaber El-Saber BatihaDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, AlBeheira, Egypt.
Eman KhalifaDepartment of Microbiology, Faculty of Veterinary Medicine, Matrouh University, Matrouh, Egypt.
Egypt Nanotechnology Center · EGAlexandria University · EGChandigarh University · INDamanhour University · EGKing Saud University · SAWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cirrhosis is a silent disease in humans and is experimentally induced by many drugs and toxins as thioacetamide (TAA) in particular, which is the typical model for experimental induction of hepatic fibrosis. Thus, the objective of the present study was to elucidate the possible protective effects of lactéol® forte (LF) and quercetin dihydrate (QD) against TAA-induced hepatic damage in male albino rats. Induction of hepatotoxicity was performed by TAA injection (200 mg/kg I/P, twice/ week) in rats. LF (1 × 10

Indexed as

Calcium CarbonateChemical and Drug Induced Liver InjuryLactoseQuercetinAnimalsCollagenDrug CombinationsFlavonoidsHumansKi-67 AntigenLiverLiver CirrhosisMaleOxidative StressRatsThioacetamideCalcium CarbonateCollagenDrug CombinationsFlavonoidsKi-67 AntigenLacteolLactoseQuercetinThioacetamidehistopathologyLactéol® forteliverquercetin dihydrateratsThioacetamide

Identifiers

PMID38534093
PMCPMC10967145
OpenAlexW4393247027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.