Evidence map›Paper›PMID 38534040›Full record

ArticleJournal of diabetes investigation2024

Characterization of the visually impaired patients with diabetes mellitus in Japan.

Yuka Sugihara, Yoshihiro Takamura, Yutaka Yamada, Masakazu Morioka, Makoto Gozawa, Kumiko Kato, Takao Hirano, Fumiko Murao, Miho Shimizu, Sentaro Kusuhara and 14 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of diabetes investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Efficacy of vitrectomy combined with and without cataract surgery for diabetic macular edema: one-year follow-up multi-center study in Japan.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Yuka SugiharaJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.ORCID https://orcid.org/0009-0000-5986-985X
Yoshihiro TakamuraJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.ORCID https://orcid.org/0000-0003-0418-6829
Yutaka YamadaDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida, Japan.
Masakazu MoriokaDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida, Japan.
Makoto GozawaDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida, Japan.
Kumiko KatoJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Takao HiranoJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Fumiko MuraoJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Miho ShimizuJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Sentaro KusuharaJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.ORCID https://orcid.org/0000-0002-6458-539X
Tomoya MurakamiJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Yuki TakenakaJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Naoko OkabeJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Tatsuya JujoJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Hiroto TerasakiJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Daisuke NagasatoJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Zhenyu DongDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Shigeo YoshidaJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Shuntaro OguraJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Kanako YasudaJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Gaku IshigookaJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Osamu SawadaJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Fumiaki HigashijimaJ-CREST (Japan Clinical REtina STudy group), Kagoshima, Japan.
Masaru InataniDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida, Japan.

Funding

Japan Society for the Promotion of Science J160000936
6 · The paper itself

Abstract

AIMS/

introductionTo conduct a multicenter survey of visually impaired patients with diabetes mellitus (DM) and to identify the physical and ocular characteristics that lead to blindness in Japan. MATERIALS AND

methodsVisually impaired patients with diabetes mellitus in Japan were divided into blind and low-vision groups according to the World Health Organization classification. Data on parameters related to diabetes mellitus and ocular complications in the right and left eyes were collected from 19 highly advanced medical facilities and compared between the two groups.

resultsAmong 408 visually impaired persons (blind group: 257, low-vision group: 151), 72.1% were under 70 years of age. The rates of neovascular glaucoma (NVG) (right eye, P = 0.041; left eye, P = 0.0031) or proliferative diabetic retinopathy (PDR) (right eye: P = 0.014, left eye: P = 0.0047) and the rate of proliferative membrane beyond half of the retinal area (right eye: P = 0.0263, left eye: P = 0.037) were significantly higher in the blind group. The direct cause of visual impairment was retinal atrophy, common in both groups. Neovascular glaucoma and diabetic macular edema were equally prevalent in the blind and low-vision groups, respectively.

conclusionsIn Japan, blind patients with diabetes mellitus are characterized by severe conditions such as neovascular glaucoma and progressive proliferative diabetic retinopathy upon their initial visit to an advanced care facility. These results highlight the importance of monitoring retinopathy through regular ophthalmological examinations, internal medicine, and appropriate therapeutic intervention.

Indexed as

BlindnessDiabetic RetinopathyPersons with Visual DisabilitiesAdultAgedAged, 80 and overDiabetes MellitusFemaleHumansJapanMaleMiddle AgedVision, LowBlindDiabetic retinopathyNeovascular glaucoma

Identifiers

PMID38534040
PMCPMC11215670

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.