Evidence map›Paper›PMID 38533959›Full record

ArticleJournal of the American Heart Association2024

Health Factors Associated With Development and Severity of Poststroke Dysphagia: An Epidemiological Investigation.

Brittany N Krekeler, Heidi J P Schieve, Jane Khoury, Lili Ding, Mary Haverbusch, Kathleen Alwell, Opeolu Adeoye, Simona Ferioloi, Jason Mackey, Daniel Woo and 11 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 2 countries.

Brittany N KrekelerDepartment of Otolaryngology-Head and Neck Surgery University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0003-0469-9181
Heidi J P SchieveWake Forest School of Medicine Winston-Salem NC USA.
Jane KhouryDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-8064-6404
Lili DingDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics University of Cincinnati College of Medicine Cincinnati OH USA.
Mary HaverbuschDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-1017-1036
Kathleen AlwellDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0003-1620-4721
Opeolu AdeoyeDepartment of Emergency Medicine Washington University School of Medicine St. Louis MO USA.ORCID 0000-0001-8666-5369
Simona FerioloiDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0001-6534-3029
Jason MackeyDepartment of Neurology Indiana University School of Medicine Indianapolis IN USA.ORCID 0000-0002-6867-8630
Daniel WooDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-2466-7155
Matthew FlahertyDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-6247-010X
Felipe De Los Rios La RosaDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0003-4465-9280
Stacie DemelDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-3000-8420
Michael StarSorkoa Medical Center Beersheva Israel.
Elisheva ColemanDepartment of Neurology University of Chicago Medicine Chicago IL USA.ORCID 0000-0002-7565-432X
Kyle WalshDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-1178-6286
Sabreena SlavinDepartment of Neurology University of Kansas Medical Center Kansas City KS USA.
Adam JasneDepartment of Neurology Yale School of Medicine New Haven CT USA.ORCID 0000-0001-9092-3607
Eva MistryDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-7426-3650
Dawn KleindorferDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0003-1361-3693
Brett KisselaDepartment of Neurology and Rehabilitation Medicine University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-9773-4013
University of Cincinnati Medical Center · USCincinnati Children's Hospital Medical Center · USBaptist Health South Florida · USIndiana University School of MedicineSoroka Medical Center · ILUniversity of Chicago · USUniversity of Kansas Medical Center · USUniversity of Michigan · USWake Forest University · USWashington University in St. Louis · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDysphagia after stroke is common and can impact morbidity and death. The purpose of this population-based study was to determine specific epidemiological and health risk factors that impact development of dysphagia after acute stroke. METHODS AND

resultsIschemic and hemorrhagic stroke cases from 2010 and 2015 were identified via chart review from the GCNKSS (Greater Cincinnati Northern Kentucky Stroke Study), a representative sample of ≈1.3 million adults from southwestern Ohio and northern Kentucky. Dysphagia status was determined on the basis of clinical assessments and necessity for alternative access to nutrition via nasogastric or percutaneous endoscopic gastrostomy tube placement. Comparisons between patients with and without dysphagia were made to determine differences in baseline characteristics and premorbid conditions. Multivariable logistic regression determined factors associated with increased risk of dysphagia. Dysphagia status was ascertained from 4139 cases (1709 with dysphagia). Logistic regression showed that increased age, Black race, higher National Institutes of Health Stroke Scale score at admission, having a hemorrhagic stroke (versus infarct), and right hemispheric stroke increased the risk of developing dysphagia after stroke. Factors associated with reduced risk included history of high cholesterol, lower prestroke modified Rankin Scale score, and white matter disease.

conclusionsThis study replicated previous findings of variables associated with dysphagia (older age, worse stroke, right-sided hemorrhagic lesions), whereas other variables identified were without clear biological rationale (eg, Black race, history of high cholesterol, and presence of white matter disease) and should be investigated in future studies to determine biological relevance and potential influence in stroke recovery.

Indexed as

Deglutition DisordersHemorrhagic StrokeLeukoencephalopathiesStrokeAdultCholesterolHumansCholesteroldysphagiafeedingstrokeswallowing

Identifiers

PMID38533959
PMCPMC11179757
OpenAlexW4393224576

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.